CAJ | 학술논문

目的：探讨胆碱能杀虫剂中毒后发生中间综合征(IMS)的相关危险因素。方法收集324例患者的一般临床资料包括年龄、性别、基础疾病,以及毒物类型、中毒途径、治疗方法、IMS的临床特征。观察IMS的发病率,并分析其相关危险因素。结果16.4%患者发生IMS,死亡率39.6%,其中男性占66.7%,且年龄>45岁是IMS进展的显著危险因素[RR 2.67,95%CI(1.31,4.72),P<0.05],而多次洗胃则是保护因素[RR 0.35,95%CI(0.11,0.79),P<0.05]。结论IMS的发生与年龄>45岁、洗胃次数多少相关,而与洗胃时机和毒物类型无关。
목적：탐토담감능살충제중독후발생중간종합정(IMS)적상관위험인소。방법수집324례환자적일반림상자료포괄년령、성별、기출질병,이급독물류형、중독도경、치료방법、IMS적림상특정。관찰IMS적발병솔,병분석기상관위험인소。결과16.4%환자발생IMS,사망솔39.6%,기중남성점66.7%,차년령>45세시IMS진전적현저위험인소[RR 2.67,95%CI(1.31,4.72),P<0.05],이다차세위칙시보호인소[RR 0.35,95%CI(0.11,0.79),P<0.05]。결론IMS적발생여년령>45세、세위차수다소상관,이여세위시궤화독물류형무관。
Objective To investigate related risk factors of intermediate syndrome (IMS) after cholinergic pesticides poisoning.Methods Collections were made on clinical data of age, gender, underlying disease, poison type, poisoning route, treatment method, and clinical characteristics of IMS in 324 cases. Morbidity of IMS was observed to analyze its related risk factors.Results There were 16.4% of the patients had IMS with the mortality rate as 39.6%, and 66.7% of them was male patients. Aging >45 years old was a significant risk factor of IMS [(RR 2.67, 95%CI(1.31, 4.72),P<0.05)], while repeated gastric lavage is the protective factor [(RR 0.35, 95%CI(0.11, 0.79),P<0.05)].Conclusion There is a correlation in IMS, age >45 years old and gastric lavage times, while IMS is not related with time of gastric lavage and poison type.