CAJ | 학술논문

目的：探讨内镜下黏膜剥离术（endoscopic submucosal dissection，ESD）治疗结直肠神经内分泌瘤的安全性和有效性。方法对重庆医科大学附属第一医院2010年9月至2014年2月43例行ESD治疗的结直肠神经内分泌瘤进行回顾性分析，评估其安全性和有效性。结果43例均在内镜下以ESD术式完整切除，2例（4.65％）术后出现迟发性出血，经内镜止血治疗痊愈；无穿孔发生；4例出现发热，使用抗生素后好转；1例（2.33％）术后1年内镜复查发现复发，行外科手术；其余42例电话或内镜随访未见复发或转移，随访时间6个月～2年（1.07±0.41）年。结论 ESD手术治疗直肠神经内分泌瘤是种简单、安全、有效的方法。
목적：탐토내경하점막박리술（endoscopic submucosal dissection，ESD）치료결직장신경내분비류적안전성화유효성。방법대중경의과대학부속제일의원2010년9월지2014년2월43례행ESD치료적결직장신경내분비류진행회고성분석，평고기안전성화유효성。결과43례균재내경하이ESD술식완정절제，2례（4.65％）술후출현지발성출혈，경내경지혈치료전유；무천공발생；4례출현발열，사용항생소후호전；1례（2.33％）술후1년내경복사발현복발，행외과수술；기여42례전화혹내경수방미견복발혹전이，수방시간6개월～2년（1.07±0.41）년。결론 ESD수술치료직장신경내분비류시충간단、안전、유효적방법。
Objective To study the efficacy and safety of endoscopic submucosal dissection ( ESD ) for colorectal neuroendocrine tumor .Methods Clinical data of 43 cases of colorectal neuroendocrine tumor receiving ESD therapy from Sep .2010 to Feb.2014 were retrospectively analyzed , and the safety and efficacy were evalua-ted.Results All the 43 cases received ESD therapy , among whom 2(4.65%)cases developed delayed bleeding and recovered after endoscopic treatment .No perforation was found .4 cases had high fever and recovered after antibiotic treatment.One case(2.33%)of recurrence was found by colonoscopy 1 year later, and underwent sur-gery.The other 42 cases were followed up for 6 months to 2 years, during which no recurrence or metastasis was found.Conclusion ESD is a simple, safe and effective modality for colorectal neuroendocrine tumor .