肺癌耐药分子机制研究进展
폐암내약분자궤제연구진전
The research progress of molecular mechanism of drug resistance in lung cancer
  • 万方数据
    转化医学杂志 전화의학잡지
    TRANSLATIONAL MEDICINE JOURNAL
    2015年 2期 110-114 ,共5页

    齐慧%苏乌云%呼群

    제혜%소오운%호군

    肺癌%化疗%耐药%分子标志物 肺癌%化療%耐藥%分子標誌物
    폐암%화료%내약%분자표지물
    Lung cancer%Chemotherapy%Drug resistance%Molecular markers
    肺癌化疗疗效差异与肿瘤的耐药密切相关，目前研究认为多种基因及分子通路参与调控肺癌细胞对化疗药物的耐药性。对肺癌耐药分子标志物的研究可预测药物治疗敏感性，对肺癌耐药的反转研究有重要意义。
    폐암화료료효차이여종류적내약밀절상관，목전연구인위다충기인급분자통로삼여조공폐암세포대화료약물적내약성。대폐암내약분자표지물적연구가예측약물치료민감성，대폐암내약적반전연구유중요의의。
    Lung cancer chemotherapy curative effects are closely associated with drug resis￣tance of tumor. Current research suggests that multiple genes and molecular pathways are involved in regulation of chemotherapy drug resistance of lung cancer cells. The study of molecular markers in lung cancer drug resistance can predict medication sensitivity, which has important significance to research on lung cancer drug resistance reversal.
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