中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2015年
12期
42-44
,共3页
总胆汁酸%肝脏疾病
總膽汁痠%肝髒疾病
총담즙산%간장질병
Total bile acid%Hepatic disease
目的：探讨血清总胆汁酸(TBA)在各类型肝脏疾病中的应用价值。方法采用循环酶法和速率法测定100例本院健康职工(对照组)和182例肝病患者血清TBA及常用肝功能指标。结果对照组的TBA为(3.9±2.9)μmol/L,各类型肝脏疾病均较对照组高(P<0.01), TBA和常用肝功能检测指标在不同类型肝脏疾病中的测定值的阳性率各有所不同,特别是肝癌和肝硬化在其他酶学指标不高时TBA阳性率分别达到96.0%和89.3%。结论TBA测定是一个敏感的肝功能检测指标,能反映肝实质损伤,与各酶学指标比较,特别适用于各类型肝脏疾病诊断、疗效观察。
目的：探討血清總膽汁痠(TBA)在各類型肝髒疾病中的應用價值。方法採用循環酶法和速率法測定100例本院健康職工(對照組)和182例肝病患者血清TBA及常用肝功能指標。結果對照組的TBA為(3.9±2.9)μmol/L,各類型肝髒疾病均較對照組高(P<0.01), TBA和常用肝功能檢測指標在不同類型肝髒疾病中的測定值的暘性率各有所不同,特彆是肝癌和肝硬化在其他酶學指標不高時TBA暘性率分彆達到96.0%和89.3%。結論TBA測定是一箇敏感的肝功能檢測指標,能反映肝實質損傷,與各酶學指標比較,特彆適用于各類型肝髒疾病診斷、療效觀察。
목적：탐토혈청총담즙산(TBA)재각류형간장질병중적응용개치。방법채용순배매법화속솔법측정100례본원건강직공(대조조)화182례간병환자혈청TBA급상용간공능지표。결과대조조적TBA위(3.9±2.9)μmol/L,각류형간장질병균교대조조고(P<0.01), TBA화상용간공능검측지표재불동류형간장질병중적측정치적양성솔각유소불동,특별시간암화간경화재기타매학지표불고시TBA양성솔분별체도96.0%화89.3%。결론TBA측정시일개민감적간공능검측지표,능반영간실질손상,여각매학지표비교,특별괄용우각류형간장질병진단、료효관찰。
Objective To investigate the application value of serum total bile acid (TBA) detection in <br> hepatic disease.Methods Enzymatic cycling assay and velocity method were applied for detection of serum TBA and common liver function index in 100 healthy staff (control group) and 182 patients with hepatic disease. Results TBA in the control group was (3.9±2.9)μmol/L, and hepatic diseases were all higher than control group (P<0.01). TBA and common liver function index had different positive rate in detection of different hepatic diseases, especially for liver cancer and liver cirrhosis with TBA positive rate as 96.0% and 89.3%.Conclusion TBA detection is a sensitive liver function index, and it can show live damage. Compared with enzymology index, it is suitable for diagnosis and effect observation in hepatic disease.
