CAJ | 학술논문

目的：比较布地奈德联合病毒唑与可必特交替雾化与布地奈德联合病毒唑或布地奈德联合可必特治疗婴幼儿毛细支气管炎的临床效果。方法90例毛细支气管炎患儿,随机分为A、B、C三组,每组30例。A组应用布地奈德联合病毒唑与可必特交替雾化治疗, B组应用布地奈德联合病毒唑进行雾化吸入, C组应用布地奈德联合可必特进行雾化吸入。比较三组患儿临床症状消失时间、住院时间以及治疗总有效率。结果 A组患儿的咳嗽、喘憋、哮鸣、肺部啰音消失时间分别为(4.3±0.4)d、(2.1±0.4)d、(2.2±0.4)d、(5.5±0.6)d,均明显少于B、C组。住院时间为(7.2±1.0)d,少于B组的(9.7±1.3)d以及C组的(9.9±1.5)d,比较差异均有统计学意义(P<0.05)。A组患儿的治疗总有效率为96.7%,明显高于B组的76.7%以及C组的73.3%,比较差异有统计学意义(P<0.05)。结论布地奈德联合病毒唑与可必特交替雾化治疗在婴幼儿毛细支气管炎中的应用可有效发挥抗炎作用,恢复气道通气功能,改善患儿咳嗽、肺部啰音及喘憋等临床症状,效果显著,具有较高应用价值。
목적：비교포지내덕연합병독서여가필특교체무화여포지내덕연합병독서혹포지내덕연합가필특치료영유인모세지기관염적림상효과。방법90례모세지기관염환인,수궤분위A、B、C삼조,매조30례。A조응용포지내덕연합병독서여가필특교체무화치료, B조응용포지내덕연합병독서진행무화흡입, C조응용포지내덕연합가필특진행무화흡입。비교삼조환인림상증상소실시간、주원시간이급치료총유효솔。결과 A조환인적해수、천별、효명、폐부라음소실시간분별위(4.3±0.4)d、(2.1±0.4)d、(2.2±0.4)d、(5.5±0.6)d,균명현소우B、C조。주원시간위(7.2±1.0)d,소우B조적(9.7±1.3)d이급C조적(9.9±1.5)d,비교차이균유통계학의의(P<0.05)。A조환인적치료총유효솔위96.7%,명현고우B조적76.7%이급C조적73.3%,비교차이유통계학의의(P<0.05)。결론포지내덕연합병독서여가필특교체무화치료재영유인모세지기관염중적응용가유효발휘항염작용,회복기도통기공능,개선환인해수、폐부라음급천별등림상증상,효과현저,구유교고응용개치。
ObjectiveTo compare the clinical effects of budesonide combined with ribavirin and combivent in alternating aerosol, budesonide combined with ribavirin, and budesonide combined with combivent in the treatment of infantile capillary bronchitis.MethodsA total of 90 children with capillary bronchitis were randomly divided into groups A, B and C, with 30 cases in each group. Group A received alternating aerosol by budesonide combined with ribavirin and combivent for treatment, group B received budesonide combined with ribavirin through aerosol inhalation, and group C received budesonide combined with combivent. Comparisons were made on symptoms disappearance time, hospital stay and total effective rate of the three groups.ResultsThe disappearance times of cough, suffocation, stridor, and rale were respectively (4.3±0.4) d, (2.1±0.4) d, (2.2±0.4) d, (5.5±0.6) d, which were all shorter than those in group B and group C. The group A had hospital stay as (7.2±1.0)d, which was shorter than (9.7±1.3) d of group B and (9.9±1.5) d of group C. The differences had statistical significance (P<0.05). The total effective rate in group A was 96.7%, which was much higher than 76.7% of group B and 73.3% of group C, and the difference had statistical significance (P<0.05).ConclusionImplement of budesonide combined with ribavirin and combivent in alternating aerosol treatment for infantile capillary bronchitis can provide effectively anti-inflammatory action. This method can rehabilitate ventilatory function and improve clinical symptoms of cough, rale and suffocation with remarkable effect. This method contains high value for application.