国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2015年
8期
1072-1074
,共3页
EB病毒%衣壳抗原%累计感染率%新发感染率
EB病毒%衣殼抗原%纍計感染率%新髮感染率
EB병독%의각항원%루계감염솔%신발감염솔
Epstein-Barr virus%capsid antigen%cumulative infection rate%recent infection rate
目的:了解EB病毒(EBV )在儿童中的感染情况及流行病学特征。方法收集2013年6月至2014年6月住院和门诊就诊的急性上呼吸道感染、支气管炎、肺炎、扁桃体炎等疾病患儿5272例的血液,采用酶联免疫吸附试验(ELISA )检测EBV衣壳抗原(VCA )抗体IgM和IgG ,分析患儿的感染情况。结果小于1岁患儿(1943例),1~<5岁患儿(2479例),5~<10岁患儿(715例),10~17岁患儿(135例)的EBV‐VCA IgM阳性率分别为5.04%、6.13%、3.92%和2.22%,EBV‐VCA IgG阳性率分别为24.60%、40.98%、62.66%和77.78%。EBV‐VCA IgG阳性率随着年龄增加有增加的趋势,且各年龄组EBV新发感染率和累计感染率比较差异均有统计学意义(P<0.05)。春季、夏季、秋季、冬季的EBV‐VCA IgM 阳性率分别为3.35%、6.26%、6. 13%和6.10%,比较差异有统计学意义(P<0.05);EBV‐VCA IgG阳性率分别为38.98%、38.38%、38.23%和39.80%,比较差异无统计学意义(P>0.05)。不同季节EBV新发感染率差异有统计学意义(P<0.05)。结论该地区 EBV的儿童感染率仍然处于较高水平,因此家长仍需提高对EB V感染预防的认识。
目的:瞭解EB病毒(EBV )在兒童中的感染情況及流行病學特徵。方法收集2013年6月至2014年6月住院和門診就診的急性上呼吸道感染、支氣管炎、肺炎、扁桃體炎等疾病患兒5272例的血液,採用酶聯免疫吸附試驗(ELISA )檢測EBV衣殼抗原(VCA )抗體IgM和IgG ,分析患兒的感染情況。結果小于1歲患兒(1943例),1~<5歲患兒(2479例),5~<10歲患兒(715例),10~17歲患兒(135例)的EBV‐VCA IgM暘性率分彆為5.04%、6.13%、3.92%和2.22%,EBV‐VCA IgG暘性率分彆為24.60%、40.98%、62.66%和77.78%。EBV‐VCA IgG暘性率隨著年齡增加有增加的趨勢,且各年齡組EBV新髮感染率和纍計感染率比較差異均有統計學意義(P<0.05)。春季、夏季、鞦季、鼕季的EBV‐VCA IgM 暘性率分彆為3.35%、6.26%、6. 13%和6.10%,比較差異有統計學意義(P<0.05);EBV‐VCA IgG暘性率分彆為38.98%、38.38%、38.23%和39.80%,比較差異無統計學意義(P>0.05)。不同季節EBV新髮感染率差異有統計學意義(P<0.05)。結論該地區 EBV的兒童感染率仍然處于較高水平,因此傢長仍需提高對EB V感染預防的認識。
목적:료해EB병독(EBV )재인동중적감염정황급류행병학특정。방법수집2013년6월지2014년6월주원화문진취진적급성상호흡도감염、지기관염、폐염、편도체염등질병환인5272례적혈액,채용매련면역흡부시험(ELISA )검측EBV의각항원(VCA )항체IgM화IgG ,분석환인적감염정황。결과소우1세환인(1943례),1~<5세환인(2479례),5~<10세환인(715례),10~17세환인(135례)적EBV‐VCA IgM양성솔분별위5.04%、6.13%、3.92%화2.22%,EBV‐VCA IgG양성솔분별위24.60%、40.98%、62.66%화77.78%。EBV‐VCA IgG양성솔수착년령증가유증가적추세,차각년령조EBV신발감염솔화루계감염솔비교차이균유통계학의의(P<0.05)。춘계、하계、추계、동계적EBV‐VCA IgM 양성솔분별위3.35%、6.26%、6. 13%화6.10%,비교차이유통계학의의(P<0.05);EBV‐VCA IgG양성솔분별위38.98%、38.38%、38.23%화39.80%,비교차이무통계학의의(P>0.05)。불동계절EBV신발감염솔차이유통계학의의(P<0.05)。결론해지구 EBV적인동감염솔잉연처우교고수평,인차가장잉수제고대EB V감염예방적인식。
Objective To investigate the situation of Epstein‐Barr virus infection in children and its epidemiologic feature .Meth‐ods Serum samples of 5 272 children with acute upper respiratory tract infection ,bronchitis ,pneumonia ,tonsillitis and so on were collected from 2013 Jun .to 2014 Jun .,and the Epstein‐Barr virus capsid antigen IgM and IgG were detected by ELISA ,and the in‐fection situation were analyzed .Results 5272 children were analyzed ,in the 0- <1 years old group(1 943 cases) ,1- <5 years old group(2 479 cases) ,5- <10 years old group(715 cases) and 10- <17 years old group(135 cases)years groups ,the positive rates of EBV‐VCA IgM were 5 .04% ,6 .13% ,3 .92% and 2 .22% respectively ,and the positive rates of EBV‐VCA IgG were 24 .60% , 40 .98% ,62 .66% and 77 .78% respectively .The positive rate of EBV‐VCA IgG was increased with the age increased ,there was statistical significance of recent infection rates and cumulative infection rates of EBV in different age group (P<0 .05) .In spring , summer ,autumn and winter ,the positive rates of EBV‐VCA IgM were 3 .35% ,6 .26% ,6 .13% and 6 .10% respectively ,there was statistical significance in different season(P< 0 .05);the positive rates of EBV‐VCA IgG were 38 .98% ,38 .38% ,38 .23% and 39 .80% respectively ,but there was no statistical significance in different season (P>0 .05) .There was statistical significance of the recent infection rates in different season (P<0 .05) .Conclusion The infection rate was still at a high level in this area ,therefore , parents still need to improve awareness on the prevention of EBV infection .