川北医学院学报
川北醫學院學報
천북의학원학보
JOURNAL OF NORTH SICHUAN MEDICAL COLLEGE
2015年
2期
243-246
,共4页
直肠癌%生存状况%相关因素%Cox比例风险回归分析
直腸癌%生存狀況%相關因素%Cox比例風險迴歸分析
직장암%생존상황%상관인소%Cox비례풍험회귀분석
Colorectal cancer%Survival%Relevant factors%Logistic regression analysis
目的：：探讨对直肠癌患者术后生存状况产生影响的相关因素,为评估疾病的预后提供可靠依据。方法：采用回顾性调查统计的方式,选取于2007年2月至2010年5月到我院普外科就诊的直肠癌患者93例,对患者或家属进行问卷调查的形式采集病史,并结合患者住院期间相关检查,统计分析患者生存时间及生存质量评分,采用Log-rank单因素分析及Cox比例风险回归分析,从而确定影响直肠癌患者术后生存状况的相关因素。结果：93例直肠癌患者中,手术后生存时间最长为7年,最短为6个月,中位时间为(1.51±0.24)年,两年生存36例,两年生存率38.71%。患者生存状况与性别、受教育程度、高血压、糖尿病、术前癌胚抗原(carcinoembryonic antigen,CEA)水平没有显著相关性(P>0.05),而与年龄、收入情况、负性情绪事件、肿瘤大小、淋巴结转移、浸润深度、手术方式、化疗与否相关(P<0.05)。结论：直肠癌患者术后生存状况与多方面因素相关,在患者诊断及治疗过程中要综合考虑各因素在疾病进展及预后中起到的作用。
目的：：探討對直腸癌患者術後生存狀況產生影響的相關因素,為評估疾病的預後提供可靠依據。方法：採用迴顧性調查統計的方式,選取于2007年2月至2010年5月到我院普外科就診的直腸癌患者93例,對患者或傢屬進行問捲調查的形式採集病史,併結閤患者住院期間相關檢查,統計分析患者生存時間及生存質量評分,採用Log-rank單因素分析及Cox比例風險迴歸分析,從而確定影響直腸癌患者術後生存狀況的相關因素。結果：93例直腸癌患者中,手術後生存時間最長為7年,最短為6箇月,中位時間為(1.51±0.24)年,兩年生存36例,兩年生存率38.71%。患者生存狀況與性彆、受教育程度、高血壓、糖尿病、術前癌胚抗原(carcinoembryonic antigen,CEA)水平沒有顯著相關性(P>0.05),而與年齡、收入情況、負性情緒事件、腫瘤大小、淋巴結轉移、浸潤深度、手術方式、化療與否相關(P<0.05)。結論：直腸癌患者術後生存狀況與多方麵因素相關,在患者診斷及治療過程中要綜閤攷慮各因素在疾病進展及預後中起到的作用。
목적：：탐토대직장암환자술후생존상황산생영향적상관인소,위평고질병적예후제공가고의거。방법：채용회고성조사통계적방식,선취우2007년2월지2010년5월도아원보외과취진적직장암환자93례,대환자혹가속진행문권조사적형식채집병사,병결합환자주원기간상관검사,통계분석환자생존시간급생존질량평분,채용Log-rank단인소분석급Cox비례풍험회귀분석,종이학정영향직장암환자술후생존상황적상관인소。결과：93례직장암환자중,수술후생존시간최장위7년,최단위6개월,중위시간위(1.51±0.24)년,량년생존36례,량년생존솔38.71%。환자생존상황여성별、수교육정도、고혈압、당뇨병、술전암배항원(carcinoembryonic antigen,CEA)수평몰유현저상관성(P>0.05),이여년령、수입정황、부성정서사건、종류대소、림파결전이、침윤심도、수술방식、화료여부상관(P<0.05)。결론：직장암환자술후생존상황여다방면인소상관,재환자진단급치료과정중요종합고필각인소재질병진전급예후중기도적작용。
Objective:To investigate related factors affecting survival of patients after colorectal cancer surgery and provide a reliable basis for assessing the prognosis of the disease. Methods: 93 cases of colorectal cancer patients were selected in February 2007 to May 2010 in our hospital by retrospective survey . Collected medical history used the questionnaires form of patients or their families combined with the relevant inspection during hospitalization. Analyse survival time and score of life quality. Determine related factors affecting survival of patients after colorectal cancer surgery using Log-rank univariate analysis and Cox proportional hazards re-gression analysis. Results:The maximum of Survival time was seven years a minimum of six months 93 cases of colorectal cancer pa-tients after surgery. the median time was (1. 51 ± 0. 24) years,36 cases of 2-year survival , 38. 71%of 2-year survival rate . Patients living conditions were not significantly correlated with gender, educational level, hypertension, diabetes, preoperative CEA levels ( P>0. 05), but with age, income, negative emotional events, tumor size, lymph node metastasis, depth of invasion, surgical approach and whether chemotherapy or not (P<0. 05) . Conclusion:Patients with colorectal cancer after surgery survival was associated with many factors. We should consider all factors in disease progression and prognosis role in the diagnosis and treatment of patients.
