国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2015年
8期
1100-1101,1103
,共3页
颈动脉超声%脑梗死%同型半胱氨酸%糖化血红蛋白%颈动脉内中膜厚度
頸動脈超聲%腦梗死%同型半胱氨痠%糖化血紅蛋白%頸動脈內中膜厚度
경동맥초성%뇌경사%동형반광안산%당화혈홍단백%경동맥내중막후도
carotid ultrasonic%cerebral infarction%homocysteine%glycosylated hemoglobin%carotid intima-media thick-ness
目的：评价颈动脉内中膜厚度（IMT）联合同型半胱氨酸（HCY）、糖化血红蛋白（HbA1c）及血脂指标检测在脑梗死中的意义。方法选取100例脑梗死患者纳入试验组，并按照病史及血糖检测结果分为糖尿病组、高血糖组及正常血糖组；另选取同期体检健康者60例纳入对照组，检测所有受试者颈动脉IM T及外周血HCY、HbA1c水平。结果试验组IM T增厚的检出率（70％）高于对照组（10％） ，且试验组的IMT及HCY与HbA1c水平均高于对照组，差异均有统计学意义（P＜0．05）；糖尿病组与高血糖组的 HbA1c水平与IMT均高于正常血糖组，差异均有统计学意义（P＜0．05）。IMT联合 HCY、HbA1c及血脂指标检测的灵敏度、特异度及准确度分别为97．1％、87．5％、94．0％。结论颈动脉超声联合脑梗死相关生化指标检测可以提高脑梗死的检出率，增加检测的灵敏度、特异度及准确度。
目的：評價頸動脈內中膜厚度（IMT）聯閤同型半胱氨痠（HCY）、糖化血紅蛋白（HbA1c）及血脂指標檢測在腦梗死中的意義。方法選取100例腦梗死患者納入試驗組，併按照病史及血糖檢測結果分為糖尿病組、高血糖組及正常血糖組；另選取同期體檢健康者60例納入對照組，檢測所有受試者頸動脈IM T及外週血HCY、HbA1c水平。結果試驗組IM T增厚的檢齣率（70％）高于對照組（10％） ，且試驗組的IMT及HCY與HbA1c水平均高于對照組，差異均有統計學意義（P＜0．05）；糖尿病組與高血糖組的 HbA1c水平與IMT均高于正常血糖組，差異均有統計學意義（P＜0．05）。IMT聯閤 HCY、HbA1c及血脂指標檢測的靈敏度、特異度及準確度分彆為97．1％、87．5％、94．0％。結論頸動脈超聲聯閤腦梗死相關生化指標檢測可以提高腦梗死的檢齣率，增加檢測的靈敏度、特異度及準確度。
목적：평개경동맥내중막후도（IMT）연합동형반광안산（HCY）、당화혈홍단백（HbA1c）급혈지지표검측재뇌경사중적의의。방법선취100례뇌경사환자납입시험조，병안조병사급혈당검측결과분위당뇨병조、고혈당조급정상혈당조；령선취동기체검건강자60례납입대조조，검측소유수시자경동맥IM T급외주혈HCY、HbA1c수평。결과시험조IM T증후적검출솔（70％）고우대조조（10％） ，차시험조적IMT급HCY여HbA1c수평균고우대조조，차이균유통계학의의（P＜0．05）；당뇨병조여고혈당조적 HbA1c수평여IMT균고우정상혈당조，차이균유통계학의의（P＜0．05）。IMT연합 HCY、HbA1c급혈지지표검측적령민도、특이도급준학도분별위97．1％、87．5％、94．0％。결론경동맥초성연합뇌경사상관생화지표검측가이제고뇌경사적검출솔，증가검측적령민도、특이도급준학도。
Objective To assess the significance of intima‐media thickness(IM T )combined with HCY ,HbA1c and blood lipid in‐dexes in patients with cerebral infarction .Methods 100 cases of patients with cerebral infarction were enrolled in the experiment group ,and were divided into normal blood glucose group ,high blood glucose group and diabetes mellitus(DM)group .60 healthy in‐dividuals were enrolled in the control group .The serum leves of HCY and HbA1c were detected ,and the IMT was determined by u‐sing ultrasonic examination .Results The positive rate of increase of IMT in the exprement group(70% ) were higher than that in the control group(10% ) ,there were significant differences between the two groups (P<0 .05) .The levels of HCY and HbA1c and IMT were higer in the exprement group compared withthose in the control group ,there was significant difference between the two groups(P<0 .05) .The serum levels of HbA1c and IMT were higher in the high blood glucose group and the DM group compared with those in the control group ,there were significant differences between the two groups (P<0 .05) .The sensitivity ,susceptibility and accuracy of IMT combined with HCY ,HbA1c and blood lipid indexes were 97 .1% ,87 .5% and 94 .0% .Conclusion The ultra‐sonic examination combined with biochemical indexes related to cerebral infarction could increase detection rate of cerebral infarc‐tion ,and the ensitivity ,susceptibility and accuracy could also increase .
