CAJ | 학술논문

目的：分析精蛋白生物合成人胰岛素注射液（预混30R）（又称诺和灵30R）联合胰岛素泵治疗糖尿病合并肺部感染的疗效及检验指标。方法选取2010年1月至2013年2月糖尿病合并肺部感染患者90例，分为对照组与观察组，各45例。对照组给予诺和灵30R治疗和常规治疗，观察组在对照组基础上加用胰岛素泵治疗，比较两组治疗后的临床效果及检验指标。结果对照组的治愈率为51．11％，总有效率为82．22％；观察组的治愈率为84．44％，总有效率为100．00％，两组治愈率及总有效率比较差异均有统计学意义（P＜0．05）。两组患者住院时间、血糖达标时间、胰岛素使用剂量、体温恢复时间、住院费用、并发症发生率，以及血钠、血钾、血酮、尿素氮水平和渗透压、PH值比较差异均有统计学意义（P＜0．05）。结论诺和灵30R联合胰岛素泵治疗糖尿病合并肺部感染临床效果满意。
목적：분석정단백생물합성인이도소주사액（예혼30R）（우칭낙화령30R）연합이도소빙치료당뇨병합병폐부감염적료효급검험지표。방법선취2010년1월지2013년2월당뇨병합병폐부감염환자90례，분위대조조여관찰조，각45례。대조조급여낙화령30R치료화상규치료，관찰조재대조조기출상가용이도소빙치료，비교량조치료후적림상효과급검험지표。결과대조조적치유솔위51．11％，총유효솔위82．22％；관찰조적치유솔위84．44％，총유효솔위100．00％，량조치유솔급총유효솔비교차이균유통계학의의（P＜0．05）。량조환자주원시간、혈당체표시간、이도소사용제량、체온회복시간、주원비용、병발증발생솔，이급혈납、혈갑、혈동、뇨소담수평화삼투압、PH치비교차이균유통계학의의（P＜0．05）。결론낙화령30R연합이도소빙치료당뇨병합병폐부감염림상효과만의。
Objective To investigate the clinical efficiency of Isophane Protamine Biosynthetic Human Insulin Injection (pre‐mixed 30R)(Novolin 30R) combined with insulin pump therapy in patients with diabetes mellitus complicated with pulmonary in‐fection ,and to analyze the detection indexes .Methods From Jan .2010 to Feb .2013 ,90 cases of patients with diabetes mellitus com‐plicated with pulmonary infection were selected and divided into the observation group and control group .The control group re‐ceived Novolin 30R treatment and conventional treatment ,the observation group were given insulin pump therapy based on the treatment of control group .The clinical efficiency and detection indexes were compared and analyzed .Results The cure rate and to‐tal effective rate were 51 .11% and 82 .22% respectively in the control group ,and were 84 .44% and 100 .00% in the observation group respectively .There were significant differences of both cure rate and total effective rate between the two groups (P<0 .05) . There were statistically significant differences of hospitalization time ,the time for reaching target of glucose ,insulin dose ,recovery time of body temperature ,hospital costs ,incidence rate of complications ,serum levels of sodium ,potassium and urea nitrogen ,os‐molality and PH value between the two groups(P<0 .05) .Conclusion The combination of Novolin 30R and insulin pump therapy could provide satisfactory clinical efficiency in patients with diabetes mellitus complicated with pulmonary infection .