检验医学与临床
檢驗醫學與臨床
검험의학여림상
JOURNAL OF LABORATORY MEDICINE AND CLINICAL SCIENCES
2015年
9期
1245-1247
,共3页
尿胰蛋白酶原-2%C反应蛋白%血清降钙素原%急性胰腺炎%感染%诊断%临床
尿胰蛋白酶原-2%C反應蛋白%血清降鈣素原%急性胰腺炎%感染%診斷%臨床
뇨이단백매원-2%C반응단백%혈청강개소원%급성이선염%감염%진단%림상
urinary trypsinogen-2%C-reactive protein%serum procalcitonin%acute pancreatitis%infec-tion%diagnosis%clinic
目的：分析尿胰蛋白酶原‐2、C反应蛋白和血清降钙素原在急性胰腺炎继发感染患者诊断中的临床价值。方法将收治的60例急性胰腺炎患者根据症状、体征和实验室检查分为继发感染组32例，未继发感染组28例，动态比较两组患者尿胰蛋白酶原‐2、C反应蛋白和血清降钙素原的变化。结果继发感染组血清C反应蛋白在入院后第1、3、5、7天明显高于未继发感染组，差异有统计学意义（P＜0．05）；继发感染组尿胰蛋白酶原‐2阳性率在入院后第5天和第7天明显高于未继发感染组，差异有统计学意义（P＜0．05）；继发感染组血清降钙素原在入院后第1、3、5、7天明显高于未继发感染组，差异有统计学意义（P＜0．05）。结论对急性胰腺炎患者及早进行尿胰蛋白酶原‐2、C反应蛋白和血清降钙素原的动态观察，能及时发现患者的病情变化，有助于急性胰腺炎继发感染的早期诊断。
目的：分析尿胰蛋白酶原‐2、C反應蛋白和血清降鈣素原在急性胰腺炎繼髮感染患者診斷中的臨床價值。方法將收治的60例急性胰腺炎患者根據癥狀、體徵和實驗室檢查分為繼髮感染組32例，未繼髮感染組28例，動態比較兩組患者尿胰蛋白酶原‐2、C反應蛋白和血清降鈣素原的變化。結果繼髮感染組血清C反應蛋白在入院後第1、3、5、7天明顯高于未繼髮感染組，差異有統計學意義（P＜0．05）；繼髮感染組尿胰蛋白酶原‐2暘性率在入院後第5天和第7天明顯高于未繼髮感染組，差異有統計學意義（P＜0．05）；繼髮感染組血清降鈣素原在入院後第1、3、5、7天明顯高于未繼髮感染組，差異有統計學意義（P＜0．05）。結論對急性胰腺炎患者及早進行尿胰蛋白酶原‐2、C反應蛋白和血清降鈣素原的動態觀察，能及時髮現患者的病情變化，有助于急性胰腺炎繼髮感染的早期診斷。
목적：분석뇨이단백매원‐2、C반응단백화혈청강개소원재급성이선염계발감염환자진단중적림상개치。방법장수치적60례급성이선염환자근거증상、체정화실험실검사분위계발감염조32례，미계발감염조28례，동태비교량조환자뇨이단백매원‐2、C반응단백화혈청강개소원적변화。결과계발감염조혈청C반응단백재입원후제1、3、5、7천명현고우미계발감염조，차이유통계학의의（P＜0．05）；계발감염조뇨이단백매원‐2양성솔재입원후제5천화제7천명현고우미계발감염조，차이유통계학의의（P＜0．05）；계발감염조혈청강개소원재입원후제1、3、5、7천명현고우미계발감염조，차이유통계학의의（P＜0．05）。결론대급성이선염환자급조진행뇨이단백매원‐2、C반응단백화혈청강개소원적동태관찰，능급시발현환자적병정변화，유조우급성이선염계발감염적조기진단。
Objective To analyze the clinical value of urine trypsinogen‐2 ,serum C‐reactive protein(CRP) and procalcitonin for the diagnosis of secondary infection in the patients with acute pancreatitis .Methods 60 cases of a‐cute pancreatitis were divided into the secondary infection group(32 cases) and the non‐secondary infection group (28 cases) according to thesymptoms ,signs and laboratory detection results .The changes of urine trypsinogen‐2 ,CRP and serum procalcitonin were dynamically compared between the two groups .Results The serum CRP level on 1 ,3 , 5 ,7 d after admission in the secondary infection group was significantly higher than that in the non-secondary infec‐tion group ,the difference was statistically significant (P<0 .05);the positive detection rate of urinary trypsinogen‐2 on 5 ,7 d after admission in the secondary infection group was significantly higher than that in the non-secondary in‐fection group ,the difference was statistically significant (P<0 .05);the serum procalcitonin level on 1 ,3 ,5 ,7 d after admission in the secondary infection group was significantly higher than that in the non-secondary infection group with statistically significant difference (P<0 .05) .Conclusion Conducting the dynamic observation on urinary tryp‐sinogen‐2 ,serum CRP and procalcitonin as soon as possible can timely find the patient′s condition changes and con‐duce to the early diagnosis of acute pancreatitis secondary infection .
