CAJ | 학술논문

目的：观察左卡尼汀治疗维持性血液透析患者并慢性心力衰竭的疗效。方法46例维持性血液透析合并慢性心力衰竭患者随机分为对照组和治疗组，每组23例，治疗组在每次透析结束前，将左卡尼汀1.0 g稀释于10 ml生理盐水中缓慢推注；对照组于透析结束前推注20 ml生理盐水。比较两组治疗前后临床疗效及心功能指标的变化。结果治疗组临床疗效较对照组明显，差异有统计学意义(P<0.05)，治疗后治疗组心功能指标改善较对照组更明显，差异有统计学意义(P<0.05)。结论左卡尼汀对维持性血液透析合并慢性心力衰竭患者疗效确切，对患者心功能有明显的改善。
목적：관찰좌잡니정치료유지성혈액투석환자병만성심력쇠갈적료효。방법46례유지성혈액투석합병만성심력쇠갈환자수궤분위대조조화치료조，매조23례，치료조재매차투석결속전，장좌잡니정1.0 g희석우10 ml생리염수중완만추주；대조조우투석결속전추주20 ml생리염수。비교량조치료전후림상료효급심공능지표적변화。결과치료조림상료효교대조조명현，차이유통계학의의(P<0.05)，치료후치료조심공능지표개선교대조조경명현，차이유통계학의의(P<0.05)。결론좌잡니정대유지성혈액투석합병만성심력쇠갈환자료효학절，대환자심공능유명현적개선。
Objective To observe the curative effect by levocarnitine for chronic cardiac failure in maintenance hemodialysis patients. Methods A total of 46 maintenance hemodialysis patients complicated with chronic cardiac failure were randomly divided into control group and treatment group, with 23 cases in each group. The treatment group received slow injection of 1.0 g levocarnitine diluted in 10 ml normal saline before the end of each hemodialysis. The control group received 20 ml normal saline through injection at the same time. Clinical effects and cardiac function indications before and after treatment were compared between the two groups. Results The treatment group had obviously better clinical effect than the control group and the difference had statistical significance (P<0.05). The treatment group also had more obvious improvement in cardiac function indications than the control group after treatment, and their difference had statistical significance (P<0.05). Conclusion Levocarnitine provides precise effect for maintenance hemodialysis patients complicated with chronic cardiac failure, along with obvious improvement in cardiac function.