浙江临床医学
浙江臨床醫學
절강림상의학
ZHEJIANG CLINICAL MEDICAL JOURNAL
2015年
3期
344-345,348
,共3页
甄涛%胡大成%陈文辉
甄濤%鬍大成%陳文輝
견도%호대성%진문휘
T2 mapping%磁共振%骶髂关节%强直性脊柱炎
T2 mapping%磁共振%骶髂關節%彊直性脊柱炎
T2 mapping%자공진%저가관절%강직성척주염
T2 mapping%Magnetic resonance%Sacroiliac joint%Ankylosing spondylitis
目的：探讨T2 mapping序列对强直性脊柱炎（AS）的早期诊断价值。方法收集有慢性炎性下腰痛症状的患者50例，其中临床诊断为AS的36例，另14例诊断为单纯慢性下腰痛（LBP）。所有患者均进行骶髂关节常规序列及8回波T2 mapping 序列的扫描，分别测量两组患者双侧骶髂骨骨性关节面下骨髓的T2值，并进行统计学分析。结果 AS组左、右侧及双侧骶骨T2值与LBP组比较差异无统计学意义。AS组左、右侧及双侧髂骨T2值均大于LBP组（P<0.05），差异有统计学意义。36例AS患者中的26例中共发现60处病灶，病灶与其周围相对正常组织比较，差异有显著性（P=0.000）。结论 T2 mapping 序列可早期发现骶髂关节骨髓T2值的改变，可对AS早期骨髓病变与单纯的慢性下腰痛患者进行鉴别，有利于患者的早期诊断。
目的：探討T2 mapping序列對彊直性脊柱炎（AS）的早期診斷價值。方法收集有慢性炎性下腰痛癥狀的患者50例，其中臨床診斷為AS的36例，另14例診斷為單純慢性下腰痛（LBP）。所有患者均進行骶髂關節常規序列及8迴波T2 mapping 序列的掃描，分彆測量兩組患者雙側骶髂骨骨性關節麵下骨髓的T2值，併進行統計學分析。結果 AS組左、右側及雙側骶骨T2值與LBP組比較差異無統計學意義。AS組左、右側及雙側髂骨T2值均大于LBP組（P<0.05），差異有統計學意義。36例AS患者中的26例中共髮現60處病竈，病竈與其週圍相對正常組織比較，差異有顯著性（P=0.000）。結論 T2 mapping 序列可早期髮現骶髂關節骨髓T2值的改變，可對AS早期骨髓病變與單純的慢性下腰痛患者進行鑒彆，有利于患者的早期診斷。
목적：탐토T2 mapping서렬대강직성척주염（AS）적조기진단개치。방법수집유만성염성하요통증상적환자50례，기중림상진단위AS적36례，령14례진단위단순만성하요통（LBP）。소유환자균진행저가관절상규서렬급8회파T2 mapping 서렬적소묘，분별측량량조환자쌍측저가골골성관절면하골수적T2치，병진행통계학분석。결과 AS조좌、우측급쌍측저골T2치여LBP조비교차이무통계학의의。AS조좌、우측급쌍측가골T2치균대우LBP조（P<0.05），차이유통계학의의。36례AS환자중적26례중공발현60처병조，병조여기주위상대정상조직비교，차이유현저성（P=0.000）。결론 T2 mapping 서렬가조기발현저가관절골수T2치적개변，가대AS조기골수병변여단순적만성하요통환자진행감별，유리우환자적조기진단。
Objective To investigate the value of T2 mapping sequence in early diagnosis of ankylosing spondylitis. Methods 50 patients with chronic inflamatory low back pain symptoms were collected in this study,out of which 36 patients were clinically diagnosed as AS and the remaining 14 as simple chronic low back pain (LBP).Images were obtained using a 1.5T MR scanner HDxt GE. The sequences included traditional sequences and 8 echo T2 mapping sequence. T2 values of subchondral bone morrow in bilateral ilium and sacrum along the sacroiliac joint were measured using GE AW4.4 post-processing workstation. An independent two sample t-test (SPSS Version 18)was used to statistically analyse the difference of T2 values between AS and LBP patients with P value of<0.05 as the level of statistically significant different. Results There was no statistically significant difference between the AS and LBP group of the mean T2 values in bilateral sacrum. The mean T2 values in bilateral iliac bone marrow of AS patients were higher than the LBP patients (P<0.05). There were 26 patients with a total of 60 lesions in 36 AS patients . The mean T2 values of the lesions were higher than the neighboring relatively normal tissues.(P<0.05). Conclusion T2 mapping sequence could detect the early change of the T2 values of bone marrow,by which early bone marrow lesions of ankylosing spondylitis could be detected and we could use this technology to differentiate simple chronic low back pain and AS patients.
