CAJ | 학술논문

目的：探讨胰岛素抵抗与女性膀胱过度活动症（OAB）的相关性。方法选择96例女性OAB患者作为观察组，同期健康体检者女性92例作为对照组。检测两组对象的空腹血糖（FPG）、三酰甘油（TG）、总胆固醇（TC）、高密度脂蛋白胆固醇（HDL‐C）、低密度脂蛋白胆固醇（LDL‐C）、空腹胰岛素（FINS）及C反应蛋白（CRP）水平，稳态模型评估法计算胰岛素抵抗指数（HOMA‐IR）。结果观察组患者腰围、体质量、体质量指数（BMI），以及患高血压人数、绝经者比例均高于对照组。观察组患者FPG、TG、FINS、CRP水平及HOMA‐IR均高于对照组，而HDL‐C水平低于对照组。两组对象TC及LDL‐C水平比较，差异无统计学意义（P＞0．05）。结论胰岛素抵抗与女性OAB有关。
목적：탐토이도소저항여녀성방광과도활동증（OAB）적상관성。방법선택96례녀성OAB환자작위관찰조，동기건강체검자녀성92례작위대조조。검측량조대상적공복혈당（FPG）、삼선감유（TG）、총담고순（TC）、고밀도지단백담고순（HDL‐C）、저밀도지단백담고순（LDL‐C）、공복이도소（FINS）급C반응단백（CRP）수평，은태모형평고법계산이도소저항지수（HOMA‐IR）。결과관찰조환자요위、체질량、체질량지수（BMI），이급환고혈압인수、절경자비례균고우대조조。관찰조환자FPG、TG、FINS、CRP수평급HOMA‐IR균고우대조조，이HDL‐C수평저우대조조。량조대상TC급LDL‐C수평비교，차이무통계학의의（P＞0．05）。결론이도소저항여녀성OAB유관。
Objective To investigate the correlation between insulin resistance with female overactive bladder (OAB) .Meth‐ods 96 female patients with OAB were selected as the observation group and contemporaneous 92 women with healthy physical ex‐amination were taken as the control group .The fasting plasma glucose (FPG) ,triglycerides (TG) ,total cholesterol (TC) ,high‐den‐sity lipoprotein (HDL‐C) ,low‐density lipoprotein (LDL‐C) ,fasting insulin (FINS) ,and C reaction protein (CRP) levels were measured in the two groups .The insulin resistance index was calculated by the homeostasis model assessment of insulin resistance (HOMA‐IR) .Results The waist circumference ,body mass ,body mass index (BMI) ,hypertension cases and proportion of meno‐pause cases in the observation group were higher than those in the control group .FPG ,TG ,FINS ,CRP levels and HOMA‐IR in the observation group were significantly higher than those in the control group ,while the HDL‐C level was lower than that in the con‐trol group .In addition ,the differences in TC and LDL‐C levels between the two groups were not statistically significant (P>0 .05) . Conclusion Insulin resistance has no correlation with female OAB .