临床医药文献电子杂志
臨床醫藥文獻電子雜誌
림상의약문헌전자잡지
Journal of Clinical Medical Literature (ElectronicEdition)
2015年
11期
2193-2194
,共2页
癫痫持续状态%咪达唑仑%地西泮
癲癇持續狀態%咪達唑崙%地西泮
전간지속상태%미체서륜%지서반
Status Epilepticus%Midazolam%Diazepam
目的：分析咪达唑仑和地西泮治疗癫痫持续状态的疗效。方法选择癫痫持续状态患者60例，随机分为两组，各30例，咪达唑仑组开始给0.15～0.2 mg/kg·h静脉注射，随后以0.06～0.6 mg/kg·h持续静脉泵入；地西泮组开始给地西泮10 mg静脉注入，随后以1.5～3μg/kg·min静脉滴注。结果咪达唑仑组有效率96.67%；地西泮组有效率66.67%。两组患者有效率比较差异有统计学意义（P＜0.05）。咪达唑仑组无明显不良反应，地西泮组3例出现呼吸抑制。结论咪达唑仑治疗癫痫持续状态疗效及安全性高于地西泮组。
目的：分析咪達唑崙和地西泮治療癲癇持續狀態的療效。方法選擇癲癇持續狀態患者60例，隨機分為兩組，各30例，咪達唑崙組開始給0.15～0.2 mg/kg·h靜脈註射，隨後以0.06～0.6 mg/kg·h持續靜脈泵入；地西泮組開始給地西泮10 mg靜脈註入，隨後以1.5～3μg/kg·min靜脈滴註。結果咪達唑崙組有效率96.67%；地西泮組有效率66.67%。兩組患者有效率比較差異有統計學意義（P＜0.05）。咪達唑崙組無明顯不良反應，地西泮組3例齣現呼吸抑製。結論咪達唑崙治療癲癇持續狀態療效及安全性高于地西泮組。
목적：분석미체서륜화지서반치료전간지속상태적료효。방법선택전간지속상태환자60례，수궤분위량조，각30례，미체서륜조개시급0.15～0.2 mg/kg·h정맥주사，수후이0.06～0.6 mg/kg·h지속정맥빙입；지서반조개시급지서반10 mg정맥주입，수후이1.5～3μg/kg·min정맥적주。결과미체서륜조유효솔96.67%；지서반조유효솔66.67%。량조환자유효솔비교차이유통계학의의（P＜0.05）。미체서륜조무명현불량반응，지서반조3례출현호흡억제。결론미체서륜치료전간지속상태료효급안전성고우지서반조。
ObjectiveTo explore the clinical effect of midazolam or diazepam in treating Status Epilepticus Methods60 Status Epilepticus patients were divided into the midazolam group (30 cases) and the diazepam group (30 cases) randomly. 0.15-0.2mg/kg midazolam was intravenous injection, followed by 0.06-0.6mg/kg/h continuous intravenous pump in midazolam group. 10mg Diazepam was intravenous injection, followed by 1.5ug/kg/min continuous intravenous drip in Diazepam group.The dose could be slightly increased if no release. The maximum dose does not exceed 3 ug/kg/min.Results Effective rate in the midazolam group was 96.67%, while it was 66.67% in Diazepam group. There was a significant difference between the two group in efficiency.(P<0.05). No significant adverse reactions was in midazolam group. 3 patients had respiratory depression in diazepam group. ConclusionIt was more effective and safe of midazolam in treating Status Epilepticus than that of diazepam.
