CAJ | 학술논문

高血压是以动脉血压持续升高为主要表现的慢性疾病，是动脉粥样硬化、冠状动脉粥样硬化性心脏病（冠心病）、脑卒中等多种心、脑血管疾病的重要危险因素。近年我国高血压患病率呈上升趋势，全国高血压患者已超3亿。颈动脉内膜中层厚度（ cIMT）是检测动脉粥样硬化的无创性指标且与高血压危险分层密切相关，同型半胱氨酸（ Hcy）通过损伤血管内皮细胞、诱导血栓形成、促进平滑肌增生等途径导致高血压病情进展并引起相应靶器官损伤。大量研究表明临床检测cIMT、Hcy对高血压病情评估及并发症预测十分重要。
고혈압시이동맥혈압지속승고위주요표현적만성질병，시동맥죽양경화、관상동맥죽양경화성심장병（관심병）、뇌졸중등다충심、뇌혈관질병적중요위험인소。근년아국고혈압환병솔정상승추세，전국고혈압환자이초3억。경동맥내막중층후도（ cIMT）시검측동맥죽양경화적무창성지표차여고혈압위험분층밀절상관，동형반광안산（ Hcy）통과손상혈관내피세포、유도혈전형성、촉진평활기증생등도경도치고혈압병정진전병인기상응파기관손상。대량연구표명림상검측cIMT、Hcy대고혈압병정평고급병발증예측십분중요。
Hypertension is an artery blood pressure rising as the main performance of chronic disease ,it is an important risk factor of atherosclerosis,coronary heart disease,stroke and other kinds of heart,brain and vascular diseases.Recently the incidence of hypertension is rising in our country .The number of hypertensive patients is more than 300 million.Carotid intima media thickness(cIMT)is a noninvasive indicator for testing the atherosclerosis.It is also closely related with hypertension risk classification .High serum homocysteine (Hcy)is an independent risk factor for hypertension.It leads to high blood pressure and corresponds target organ complications by injuring the vascular endothelial cells,promoting intravascular thrombosis,and causing vascular smooth muscle hyperplasia.There are many researches show that it is very important to test cIMT and Hcy on hypertensive patients for disease assessment and the prediction of complications .