医学综述
醫學綜述
의학종술
MEDICAL RECAPITULATE
2015年
7期
1172-1174
,共3页
田文玲(综述)%李昀生(审校)
田文玲(綜述)%李昀生(審校)
전문령(종술)%리윤생(심교)
牙周炎%风湿病%类风湿关节炎%抗瓜氨酸蛋白抗体
牙週炎%風濕病%類風濕關節炎%抗瓜氨痠蛋白抗體
아주염%풍습병%류풍습관절염%항과안산단백항체
Periodontitis%Rheumatoid arthritis%Anti-citrullinated protein anti-bodies
临床统计证实了牙周炎与类风湿关节炎( RA)之间存在统计学意义上的相关性。牙周炎是最常见的口腔疾病之一,其特征是牙周附着和牙槽骨受到炎症破坏,而风湿性或其他炎症系统性疾病将促使牙周炎产生及其发展。近期的研究表明,RA较特异的因子———抗瓜氨酸蛋白抗体在牙周炎发病之前即可检测出来,能在一定程度上说明两种疾病的病理相关性,这一研究结论将为这两种疾病的预防和治疗提供更多的理论依据。
臨床統計證實瞭牙週炎與類風濕關節炎( RA)之間存在統計學意義上的相關性。牙週炎是最常見的口腔疾病之一,其特徵是牙週附著和牙槽骨受到炎癥破壞,而風濕性或其他炎癥繫統性疾病將促使牙週炎產生及其髮展。近期的研究錶明,RA較特異的因子———抗瓜氨痠蛋白抗體在牙週炎髮病之前即可檢測齣來,能在一定程度上說明兩種疾病的病理相關性,這一研究結論將為這兩種疾病的預防和治療提供更多的理論依據。
림상통계증실료아주염여류풍습관절염( RA)지간존재통계학의의상적상관성。아주염시최상견적구강질병지일,기특정시아주부착화아조골수도염증파배,이풍습성혹기타염증계통성질병장촉사아주염산생급기발전。근기적연구표명,RA교특이적인자———항과안산단백항체재아주염발병지전즉가검측출래,능재일정정도상설명량충질병적병리상관성,저일연구결론장위저량충질병적예방화치료제공경다적이론의거。
Clinical statistics has confirmed that there is statistical correlation between periodontitis and rheumatoid arthritis.Periodontitis is the most common oral disease,characterized by the inflammatory destruc-tion of periodontal attachment and alveolar bone .The existence of a rheumatic or other inflammatory systemic disease may promote both the incidence and development of periodontitis .Recent studies have shown that anti-citrullinated protein antibodies (ACPA),which are highly specific to rheumatoid arthritis,can be detec-ted before the incidence of periodontitis,such result can partly explain the pathologic correlation between these two diseases,and will provide theoretical basis for the prevention and treatment of the two diseases .