重庆医学
重慶醫學
중경의학
CHONGQING MEDICAL JOURNAL
2015年
10期
1328-1329,1333
,共3页
儿童%手术后期间%烦躁%二异丙酚%不同剂量%治疗结果
兒童%手術後期間%煩躁%二異丙酚%不同劑量%治療結果
인동%수술후기간%번조%이이병분%불동제량%치료결과
child%postoperative period%dysphoria%propofol%different doses%treatment outcome
目的：探讨不同剂量丙泊酚对预防小儿术后躁动的影响。方法选择2012年9月至2013年6月在泸州医学院附属中医院择期行斜疝修补术的小儿60例，分为Ⅰ、Ⅱ、Ⅲ3组，3组患儿均采用七氟醚进行全身麻醉，术后分别采用0．10 mL／kg 的0．90％氯化钠注射液静脉注射、1．00 mg／kg 丙泊酚静脉注射1次和1．00 mg／kg 丙泊酚静脉注射2次，比较 3组患儿术后30 min 内躁动的发生率，并对患儿进行麻醉苏醒烦躁评分、Aldrete 改良评分和苏醒时间及出室时间比较。结果Ⅰ、Ⅱ、Ⅲ组患儿30 min 内躁动发生率分别为65．00％、25．00％及15．00％，3组患儿比较差异有统计学意义（P ＜0．05）；3组患儿在麻醉苏醒烦躁评分、Aldrete 改良评分和苏醒时间比较，差异有统计学意义（P ＜0．05），3组患儿出室时间比较，差异无统计学意义（P ＞0．05）。结论术后采用1．00 mg／kg 丙泊酚静脉注射2次，预防小儿术后躁动效果明显，安全性好，具有重要的临床参考价值。
目的：探討不同劑量丙泊酚對預防小兒術後躁動的影響。方法選擇2012年9月至2013年6月在瀘州醫學院附屬中醫院擇期行斜疝脩補術的小兒60例，分為Ⅰ、Ⅱ、Ⅲ3組，3組患兒均採用七氟醚進行全身痳醉，術後分彆採用0．10 mL／kg 的0．90％氯化鈉註射液靜脈註射、1．00 mg／kg 丙泊酚靜脈註射1次和1．00 mg／kg 丙泊酚靜脈註射2次，比較 3組患兒術後30 min 內躁動的髮生率，併對患兒進行痳醉囌醒煩躁評分、Aldrete 改良評分和囌醒時間及齣室時間比較。結果Ⅰ、Ⅱ、Ⅲ組患兒30 min 內躁動髮生率分彆為65．00％、25．00％及15．00％，3組患兒比較差異有統計學意義（P ＜0．05）；3組患兒在痳醉囌醒煩躁評分、Aldrete 改良評分和囌醒時間比較，差異有統計學意義（P ＜0．05），3組患兒齣室時間比較，差異無統計學意義（P ＞0．05）。結論術後採用1．00 mg／kg 丙泊酚靜脈註射2次，預防小兒術後躁動效果明顯，安全性好，具有重要的臨床參攷價值。
목적：탐토불동제량병박분대예방소인술후조동적영향。방법선택2012년9월지2013년6월재로주의학원부속중의원택기행사산수보술적소인60례，분위Ⅰ、Ⅱ、Ⅲ3조，3조환인균채용칠불미진행전신마취，술후분별채용0．10 mL／kg 적0．90％록화납주사액정맥주사、1．00 mg／kg 병박분정맥주사1차화1．00 mg／kg 병박분정맥주사2차，비교 3조환인술후30 min 내조동적발생솔，병대환인진행마취소성번조평분、Aldrete 개량평분화소성시간급출실시간비교。결과Ⅰ、Ⅱ、Ⅲ조환인30 min 내조동발생솔분별위65．00％、25．00％급15．00％，3조환인비교차이유통계학의의（P ＜0．05）；3조환인재마취소성번조평분、Aldrete 개량평분화소성시간비교，차이유통계학의의（P ＜0．05），3조환인출실시간비교，차이무통계학의의（P ＞0．05）。결론술후채용1．00 mg／kg 병박분정맥주사2차，예방소인술후조동효과명현，안전성호，구유중요적림상삼고개치。
Objective To explore the effects of the different doses of propofol for preventing postoperative agitation in chil-dren.Methods 60 children cases undergoing elective indirect inguinal hernia hernioplasty were selected in the Affiliated Hospital of Traditional Chinese Medicine,Luzhou Medical College from June 2011 to April 2011 and randomly divided into the group Ⅰ,Ⅱ andⅢ.The three groups were performed the general anesthesia with sevoflurane and postoperatively given 0.90% sodium chloride in-jection 0.10 mL/kg by intravenous injection,propofol 1.00 mg/kg by once intravenous injection and propofol 1.00 mg/kg by twice intravenous injection,respectively.The occurrence rate of postoperative agitation within 30 min was compared among 3 groups.The anesthesia recovery agitation score,improved Aldrete score,awakening time and time out of the operation room were also compared. Results The occurrence rates of agitation within postoperative 30 min in the group Ⅰ,Ⅱ and Ⅲ were 65.00%,65.00% and 15.00% respectively,the difference among three groups was statistically significant (P <0.05);the anesthesia recovery agitation score,improved Aldrete score and awakening time had statistically significant differences among 3 groups (P <0.05),the time out of the operation room had no statistical difference(P > 0.05).Conclusion Postoperative twice intravenous injection of propofol 1.00 mg/kg has obvious effect and good safety for preventing the postoperative agitation in children,which has important clinical reference value.
