重庆医学
重慶醫學
중경의학
CHONGQING MEDICAL JOURNAL
2015年
10期
1347-1348,1351
,共3页
顾丽丽%张学学%章勇%刘小健%曹新添%张达颖
顧麗麗%張學學%章勇%劉小健%曹新添%張達穎
고려려%장학학%장용%류소건%조신첨%장체영
腰骶丛%交感神经节%射频热凝%普瑞巴林%复合性局部疼痛综合征
腰骶叢%交感神經節%射頻熱凝%普瑞巴林%複閤性跼部疼痛綜閤徵
요저총%교감신경절%사빈열응%보서파림%복합성국부동통종합정
lumbosacral plexus%sympathetic ganglia%radiofrequency thermocoagulation%pregabalin%complex regional pain syndrome
目的：观察腰交感神经节射频热凝联合普瑞巴林（PGB）治疗复合性局部疼痛综合征（CRPS）的临床疗效和安全性。方法选择26例下肢 CRPS 患者，给予腰交感神经节射频热凝术联合口服 PGB。采用视觉模拟评分（VAS）和睡眠质量评分（QS）评估并记录治疗前及治疗后1、7、14、28、56 d 的疼痛变化，并记录患肢皮肤温度变化及不良反应的发生情况。结果与治疗前相比，患者治疗后 VAS 和 QS 评分明显下降（P＜0．05），患肢皮肤温度明显升高（P ＜0．05），治疗后28、56 d 总有效率为88．46％、96．15％。不良反应主要为头晕和嗜睡，均无血管、神经及腹腔脏器损伤等严重并发症的发生。结论腰交感神经节射频热凝联合 PGB 治疗 CRPS 可迅速缓解患者疼痛，改善患者睡眠质量和生活质量。
目的：觀察腰交感神經節射頻熱凝聯閤普瑞巴林（PGB）治療複閤性跼部疼痛綜閤徵（CRPS）的臨床療效和安全性。方法選擇26例下肢 CRPS 患者，給予腰交感神經節射頻熱凝術聯閤口服 PGB。採用視覺模擬評分（VAS）和睡眠質量評分（QS）評估併記錄治療前及治療後1、7、14、28、56 d 的疼痛變化，併記錄患肢皮膚溫度變化及不良反應的髮生情況。結果與治療前相比，患者治療後 VAS 和 QS 評分明顯下降（P＜0．05），患肢皮膚溫度明顯升高（P ＜0．05），治療後28、56 d 總有效率為88．46％、96．15％。不良反應主要為頭暈和嗜睡，均無血管、神經及腹腔髒器損傷等嚴重併髮癥的髮生。結論腰交感神經節射頻熱凝聯閤 PGB 治療 CRPS 可迅速緩解患者疼痛，改善患者睡眠質量和生活質量。
목적：관찰요교감신경절사빈열응연합보서파림（PGB）치료복합성국부동통종합정（CRPS）적림상료효화안전성。방법선택26례하지 CRPS 환자，급여요교감신경절사빈열응술연합구복 PGB。채용시각모의평분（VAS）화수면질량평분（QS）평고병기록치료전급치료후1、7、14、28、56 d 적동통변화，병기록환지피부온도변화급불량반응적발생정황。결과여치료전상비，환자치료후 VAS 화 QS 평분명현하강（P＜0．05），환지피부온도명현승고（P ＜0．05），치료후28、56 d 총유효솔위88．46％、96．15％。불량반응주요위두훈화기수，균무혈관、신경급복강장기손상등엄중병발증적발생。결론요교감신경절사빈열응연합 PGB 치료 CRPS 가신속완해환자동통，개선환자수면질량화생활질량。
Objective To observe the efficacy and safety of radiofrequency thermocoagulation of lumbar sympathetic ganglia combined with pregabalin in the treatment of complex regional pain syndrome(CRPS).Methods 26 patients with lower limb CRPS were selected and treated by the radiofrequency thermocoagulation of lumbar sympathetic ganglia combined with oral pregabalin capsule.The visual analogue scale (VAS)and the quality of sleep(QS)were adopted to evaluate the pain change before treatment and on 1,7,14,28,56 d after treatment.The temperature change of lower limb skin and the occurrence situation of adverse reactions were recorded.Results Compared with before treatment,the scores of VAS and QS at different time points after treatment were decreased significantly (P <0.05),the skin temperature of affected lower limb after treatment was increased significantly (P <0.05).The total effective rates on 28,56 d after treatment were 88.46% and 96.15% respectively.The adverse reactions were mainly dizziness and somnolence.No severe complications such as vascular,neural and intra-abdominal organs injury were found in the treatment process.Conclusion The radiofrequency thermocoagulation of lumbar sympathetic ganglia combined with pregabalin in the treatment of CRPS can rapidly alleviate pain,improve the patients′quality of sleep and living.
