岭南现代临床外科
嶺南現代臨床外科
령남현대림상외과
LINGNAN MODERN CLINICS IN SURGERY
2015年
2期
172-174
,共3页
胶质瘤%手术%放疗%化疗%伽玛刀
膠質瘤%手術%放療%化療%伽瑪刀
효질류%수술%방료%화료%가마도
Glioma%Operation%Radiotherapy%Chemotherapy%Gamma knife
目的：分析高级别胶质瘤术后辅助治疗（伽玛刀、常规分割放射治疗、化疗以及同步放化疗）对其平均复发时间的影响。评估辅助治疗对高级别胶质瘤的临床疗效。方法收集德阳市人民医院神经外科2008年1月～2013年12月间收治的具有完整病历资料的高级别脑胶质瘤复发患者64例。分为28例单纯手术治疗患者（A 组）；36例行辅助治疗患者（B 组）包括：10例术后行伽玛刀治疗患者（Ⅰ组）；4例术后行常规分割放射治疗患者（Ⅱ组）；3例术后行化疗患者（Ⅲ组）；19例术后行同步放化疗患者（Ⅳ组）。分析不同组别平均复发时间。结果 A 组平均复发时间为7．804个月；B 组平均复发时间为13．431个月；Ⅰ组平均复查时间为11．450个月；Ⅱ组平均复发时间为8．000个月；Ⅲ组平均复发时间为13．167个月；Ⅳ组平均复发时间为15．659个月。A 组与B 组及Ⅳ组之间有统计学差异。 A 组与Ⅰ组、Ⅱ组及Ⅲ组间无统计学差异。结论同步放化疗对高级别胶质瘤的平均复发时间有一定延缓作用。
目的：分析高級彆膠質瘤術後輔助治療（伽瑪刀、常規分割放射治療、化療以及同步放化療）對其平均複髮時間的影響。評估輔助治療對高級彆膠質瘤的臨床療效。方法收集德暘市人民醫院神經外科2008年1月～2013年12月間收治的具有完整病歷資料的高級彆腦膠質瘤複髮患者64例。分為28例單純手術治療患者（A 組）；36例行輔助治療患者（B 組）包括：10例術後行伽瑪刀治療患者（Ⅰ組）；4例術後行常規分割放射治療患者（Ⅱ組）；3例術後行化療患者（Ⅲ組）；19例術後行同步放化療患者（Ⅳ組）。分析不同組彆平均複髮時間。結果 A 組平均複髮時間為7．804箇月；B 組平均複髮時間為13．431箇月；Ⅰ組平均複查時間為11．450箇月；Ⅱ組平均複髮時間為8．000箇月；Ⅲ組平均複髮時間為13．167箇月；Ⅳ組平均複髮時間為15．659箇月。A 組與B 組及Ⅳ組之間有統計學差異。 A 組與Ⅰ組、Ⅱ組及Ⅲ組間無統計學差異。結論同步放化療對高級彆膠質瘤的平均複髮時間有一定延緩作用。
목적：분석고급별효질류술후보조치료（가마도、상규분할방사치료、화료이급동보방화료）대기평균복발시간적영향。평고보조치료대고급별효질류적림상료효。방법수집덕양시인민의원신경외과2008년1월～2013년12월간수치적구유완정병력자료적고급별뇌효질류복발환자64례。분위28례단순수술치료환자（A 조）；36례행보조치료환자（B 조）포괄：10례술후행가마도치료환자（Ⅰ조）；4례술후행상규분할방사치료환자（Ⅱ조）；3례술후행화료환자（Ⅲ조）；19례술후행동보방화료환자（Ⅳ조）。분석불동조별평균복발시간。결과 A 조평균복발시간위7．804개월；B 조평균복발시간위13．431개월；Ⅰ조평균복사시간위11．450개월；Ⅱ조평균복발시간위8．000개월；Ⅲ조평균복발시간위13．167개월；Ⅳ조평균복발시간위15．659개월。A 조여B 조급Ⅳ조지간유통계학차이。 A 조여Ⅰ조、Ⅱ조급Ⅲ조간무통계학차이。결론동보방화료대고급별효질류적평균복발시간유일정연완작용。
Objective To investigate the effects of postoperative concomitant therapies of high-grade glioma (gamma knife, radiotherapy, chemotherapy, synchronization chemoradiation) on delaying median relapse time and assess the clinical significance of postoperative concomitant therapy. Methods Sixty-four patients with recurring high-grade glioma patients in Deyang People’s Hospital between Jan 2008 to Dec 2013 were included in the study. Of them , 28 patients were treated with only operation (A group), 36 patients treated with postoperative concomitant therapy (B group). In B group, 10 patients were treated with postoperative gamma knife (I group), 4 patients received postoperative radiotherapy (Ⅱ group ) , 3 patients received postoperative chemotherapy (Ⅲ group ) , 19 patients were treated with postoperative synchronization chemoradiation (Ⅳ group). Analyse the median relapse time among the groups. Results The median relapse time is 7.804 months in A group , 13.431 months in B group; 11.450 months in Ⅰ group, 8.000 months in Ⅱ group; 13.167 months in Ⅲgroup, 15.659 months in Ⅳ group. It has statistical significance between A group and B group, also between A group and Ⅳ group. But it has no statistical significance among A group and other groups. Conclusion Synchronization chemoradiation is effective for postponing median relapse time of High-grade glioma.
