CAJ | 학술논문

硫双加氧酶在线粒体硫化物氧化过程中催化过硫化物、氧气和水反应形成亚硫酸盐，其功能丧失会导致体内硫化物积累产生多种疾病。本文通过对国内外文献的研究分析对硫双加氧酶的基因结构特征，催化活性和催化机制等进行了全面的综述，为进一步研究硫双加氧酶和拓展人们对硫化物代谢分子机制提供了有价值的参考。
류쌍가양매재선립체류화물양화과정중최화과류화물、양기화수반응형성아류산염，기공능상실회도치체내류화물적루산생다충질병。본문통과대국내외문헌적연구분석대류쌍가양매적기인결구특정，최화활성화최화궤제등진행료전면적종술，위진일보연구류쌍가양매화탁전인문대류화물대사분자궤제제공료유개치적삼고。
In the mitochondrial sulfide oxidation ,the function of sulfur dioxygenase (SDO) is to oxidize persul‐fide to sulfite using O2 and H2 O .The loss of its function results in the accumulation of sulfide in vivo ,which leads to many diseases .This paper reviews the SDO gene characteristics ,SDO catalytic activity and catalytic mecha‐nisms ,which is willing to offer valuable references for the further study of SDO and extensional understanding of sulfide metabolism mechanisms .