CAJ | 학술논문

目的：观察抗休克合剂治疗烧伤休克的临床效果。方法30例重度烧伤休克患者随机分为对照组和治疗组两组各15例。对照组予常规抗休克治疗，治疗组在对照组治疗基础上鼻饲抗休克合剂。观察并记录两组患者复苏前，复苏后24 h、48 h、72 h的血乳酸值、碱剩余，心率、尿量及补液量等体征和临床症状情况。结果治疗组第1个24 h、第2个24 h补液量均低于对照组（均P<0.05）；第1个24 h及第2个24 h每小时尿量与对照组相当（P>0.05），但第3个24 h每小时尿量多于对照组（P<0.05）。治疗组在复苏后第1个24 h、第2个24 h及第3个24 h心率改善明显优于对照组（均P<0.05）。两组入院时血乳酸及碱剩余均相近（P>0.05）；入院1d、2d及3d治疗组血乳酸值均较对照组明显降低（均P<0.05）；而入院1d、2d及3d治疗组碱剩余显著高于对照组（均P<0.01）。结论严重烧伤患者常规液体复苏同时加用抗休克合剂，有利于患者安全渡过休克期，降低死亡率。
목적：관찰항휴극합제치료소상휴극적림상효과。방법30례중도소상휴극환자수궤분위대조조화치료조량조각15례。대조조여상규항휴극치료，치료조재대조조치료기출상비사항휴극합제。관찰병기록량조환자복소전，복소후24 h、48 h、72 h적혈유산치、감잉여，심솔、뇨량급보액량등체정화림상증상정황。결과치료조제1개24 h、제2개24 h보액량균저우대조조（균P<0.05）；제1개24 h급제2개24 h매소시뇨량여대조조상당（P>0.05），단제3개24 h매소시뇨량다우대조조（P<0.05）。치료조재복소후제1개24 h、제2개24 h급제3개24 h심솔개선명현우우대조조（균P<0.05）。량조입원시혈유산급감잉여균상근（P>0.05）；입원1d、2d급3d치료조혈유산치균교대조조명현강저（균P<0.05）；이입원1d、2d급3d치료조감잉여현저고우대조조（균P<0.01）。결론엄중소상환자상규액체복소동시가용항휴극합제，유리우환자안전도과휴극기，강저사망솔。
Objective:To observe the clinical effect of anti-shock mixture in the treatment of burn shock. Methods:30 patients of severe burn shock were randomly divided into a treatment group and control group, with 15 patients in each group. All the patients were treated by the same conventional anti-shock treatment,and the treatment group was additionally given nasogastric Kangxiuke mixture. Observe and record patients before re?covery,24,48,72 h after recovery of blood lactic acid,base excess,heart rate,urinary volume and amount of re?hydration and the change of clinical symptoms of two groups were observe and recorded. Results:The experi?mental group blood lactic acid were significantly lower than the control group(P<0.05);Base excess was signifi?cantly higher than control group(P<0.01);The experimental group per hour urine significantly were more than the control group(P<0.05);Heart rate improved significantly better than control group(P<0.05). On the first 24 h in experimental group rehydration and two 24 h rehydration amount was lower than that of the control group (P< 0.05). Conclusion:Severe burn patients conventionalfluid resuscitation of shock with anti-shock mixture at the same time,is conducive to patient safety through the shock stage and reduce the death rate.