CAJ | 학술논문

目的：探讨两种部分脾栓塞方法治疗原发性脾功能亢进的临床疗效。方法：62例肝硬化并发门脉高压及脾功能亢进患者分为外周栓塞组和下极栓塞组，分别行部分性脾栓塞术（ PSE ）。于术前3 d、术后2周采集外周血，对比两组术前、术后肝功能和外周血象的变化以及并发症的发生情况。结果：两组术前及术后2周比较肝功能无明显变化。两组栓塞术后外周血白细胞、血小板都较术前升高，其中A组较B组效果更为明显，两组差异有统计学意义（ P＜0.05）；A组并发症的发生率大于B组。结论：外周栓塞法比脾脏下极栓塞法缓解脾功能亢进效果更为明显，但相应的并发症也更容易出现，临床实际应用中应权衡选择。
목적：탐토량충부분비전새방법치료원발성비공능항진적림상료효。방법：62례간경화병발문맥고압급비공능항진환자분위외주전새조화하겁전새조，분별행부분성비전새술（ PSE ）。우술전3 d、술후2주채집외주혈，대비량조술전、술후간공능화외주혈상적변화이급병발증적발생정황。결과：량조술전급술후2주비교간공능무명현변화。량조전새술후외주혈백세포、혈소판도교술전승고，기중A조교B조효과경위명현，량조차이유통계학의의（ P＜0.05）；A조병발증적발생솔대우B조。결론：외주전새법비비장하겁전새법완해비공능항진효과경위명현，단상응적병발증야경용역출현，림상실제응용중응권형선택。
Objective: To discuss the clinical outcomes related to portal hypertension of cirrhosis with two different partial splenic embolization ( PSE ) . Methods: Sixty-two patients with hypersplenism and portal hypertension complicated with post-hepatic cirrhosis were divided into two groups and received PSE.Liver function, peripheral blood examination were tested regularly pre-PSE and post-PSE, complications were observed. Results:There was no significant changes in liver function of the two groups.Peripheral white blood cells, platelets of two groups all increased than the preoperative after embolization.There were statistically significant difference between the two groups.Those complications included hydrothorax, ascites, left lower pneumonia, and was more serious in group A.Conclusion: The clinical effect of group A is more obvious than group B in hypersplenism treatment, but the corresponding complications are also more likely to report, the clinical applications should be balanced.