CAJ | 학술논문

目的：在4 Hz谐振频率下不同干预方式对兔抗谐振后观察血清代谢标志物特异性碱性磷酸酶（BALP）、6－酮前列腺素1α（6－keto－PGF 1α）的含量及丙二醛（MDA）含量的影响。方法75只新西兰兔随机均分为正常对照组、造模对照组及3个谐振干预实验组，每组15只，分别于实验的2、4、6周每组中随机抽取5只在清晨空腹下经耳缘静脉穿刺抽取5 ml静脉血，装于抗凝试管，测定血清中特异性碱性磷酸酶（BALP）、6－酮前列腺素1α（6－keto－PGF 1α）及丙二醛（MDA）含量并观察动态变化。结果与正常对照组和谐振干预3组比较，造模对照组、谐振干预1、2组BALP、6－keto－PGF 1α第4周开始升高，MDA含量从第6周开始升高且差异显著（P＜0．05）。与造模对照组相比，正常对照组、谐振干预3组BALP、6－keto－PGF 1α和MDA的含量在第4、6周降低且谐振干预1、2组与谐振干预3组同期相比差异显著（P＜0．05）。结论不同干预对谐振引起的下腰痛早期防治具有重要参考价值，尤以PEP加工成大小不同空心棉球组成表面凹凸不平的坐垫对于防治下腰痛发生具有重要意义。
목적：재4 Hz해진빈솔하불동간예방식대토항해진후관찰혈청대사표지물특이성감성린산매（BALP）、6－동전렬선소1α（6－keto－PGF 1α）적함량급병이철（MDA）함량적영향。방법75지신서란토수궤균분위정상대조조、조모대조조급3개해진간예실험조，매조15지，분별우실험적2、4、6주매조중수궤추취5지재청신공복하경이연정맥천자추취5 ml정맥혈，장우항응시관，측정혈청중특이성감성린산매（BALP）、6－동전렬선소1α（6－keto－PGF 1α）급병이철（MDA）함량병관찰동태변화。결과여정상대조조화해진간예3조비교，조모대조조、해진간예1、2조BALP、6－keto－PGF 1α제4주개시승고，MDA함량종제6주개시승고차차이현저（P＜0．05）。여조모대조조상비，정상대조조、해진간예3조BALP、6－keto－PGF 1α화MDA적함량재제4、6주강저차해진간예1、2조여해진간예3조동기상비차이현저（P＜0．05）。결론불동간예대해진인기적하요통조기방치구유중요삼고개치，우이PEP가공성대소불동공심면구조성표면요철불평적좌점대우방치하요통발생구유중요의의。
Objective To observe the effects of different interventions of syntony under 4 Hz on the markers in serum such as alkaline phosphatase (BALP),6-keto prostaglandin 1α (6-keto-PGF 1α) and malondialdehyde (MDA) in rabbits. Methods Sevety-five New Zealand white rabbits were randomly divided into five groups:control group,matched control group, Ⅰ model group, Ⅱ model group and Ⅲ model group,n=15 for each. The activity of BALP,6-keto-PGF 1α and MDA in serum were determined at the 2nd,4th and 6th week after treatment. Results Compared with the control group and Ⅲ model group,BALP,6-keto-PGF 1α and MDA in the matched control group, Ⅰ model group and Ⅱ model group ascended at the 4th and 6th week (P<0.05). Compared with matched control group,BALP and 6-keto-PGF 1α in the control group and Ⅲ model group were reduced since the 4th week,MDA were reduced since the 6th week (P<0.05). Conclusion The intervention of syntony has very important reference value for early prevention of low back pain caused by syntony.