中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
10期
7-9
,共3页
陈征%陈文明%任卫琼%李文莉
陳徵%陳文明%任衛瓊%李文莉
진정%진문명%임위경%리문리
紫草%β,β'-二甲基丙烯酰阿卡宁%浸出物
紫草%β,β'-二甲基丙烯酰阿卡寧%浸齣物
자초%β,β'-이갑기병희선아잡저%침출물
A rnebiae Radix%β,β-dimethylacrylalkannin%Extraction
目的：研究不同市场紫草的相关质量。方法收集10个市场紫草，采用Agilent ZORBAX Extend-C18(4.6 mm×250 mm，5μm)色谱柱，以乙腈-水-甲酸(70：30：0.05)为流动相，检测波长275 nm，柱温25℃，1 ml/min，测定不同市场紫草β，β'-二甲基丙烯酰阿卡宁的含量；采用冷浸法，以95%乙醇为溶剂，测定不同市场紫草浸出物的含量。结果10个不同市场紫草β，β'-二甲基丙烯酰阿卡宁和浸出物含量差异明显，且只有两个市场紫草β，β'-二甲基丙烯酰阿卡宁的含量>0.30%。结论当前市售紫草质量不一，而且很多市场紫草质量令人担忧。
目的：研究不同市場紫草的相關質量。方法收集10箇市場紫草，採用Agilent ZORBAX Extend-C18(4.6 mm×250 mm，5μm)色譜柱，以乙腈-水-甲痠(70：30：0.05)為流動相，檢測波長275 nm，柱溫25℃，1 ml/min，測定不同市場紫草β，β'-二甲基丙烯酰阿卡寧的含量；採用冷浸法，以95%乙醇為溶劑，測定不同市場紫草浸齣物的含量。結果10箇不同市場紫草β，β'-二甲基丙烯酰阿卡寧和浸齣物含量差異明顯，且隻有兩箇市場紫草β，β'-二甲基丙烯酰阿卡寧的含量>0.30%。結論噹前市售紫草質量不一，而且很多市場紫草質量令人擔憂。
목적：연구불동시장자초적상관질량。방법수집10개시장자초，채용Agilent ZORBAX Extend-C18(4.6 mm×250 mm，5μm)색보주，이을정-수-갑산(70：30：0.05)위류동상，검측파장275 nm，주온25℃，1 ml/min，측정불동시장자초β，β'-이갑기병희선아잡저적함량；채용랭침법，이95%을순위용제，측정불동시장자초침출물적함량。결과10개불동시장자초β，β'-이갑기병희선아잡저화침출물함량차이명현，차지유량개시장자초β，β'-이갑기병희선아잡저적함량>0.30%。결론당전시수자초질량불일，이차흔다시장자초질량령인담우。
Objective To study the related quality of Arnebiae Radix from different market. Methods Arnebiae Radix from 10 markets were collected,Agilent ZORBAX Extend-C18 (4.6 mmí250 mm,5 μm) chromatographic column was used,acetonitrile-water-formic acid (70:30:0.05) was as the mobile phase,the detection wavelength was 275 nm,column temperature was 25℃,1 ml/min,the content of β,β-dimethylacrylalkannin in A rnebiae Radix from different market was determinated;cooling extracting method was used,95% ethanol was as solvent,the extraction content of Arnebiae Radix from different market was determinated. Results The β,β-dimethylacrylalkannin content and extraction content of A rnebiae Radix from 10 different markets had obvious differences,and there were only two markets β,β-dimethylacry-lalkannin content of Arnebiae Radix more than 0.30%. Conclusion The quality of commercially available Arnebiae Radix is different,and the quality of A rnebiae Radix in a lot of markets is worrying.
