CAJ | 학술논문

目的：观察薄荷素油胶囊联合多潘立酮治疗胃手术后胆汁反流性胃炎的临床疗效。方法选择胃手术后胆汁反流性胃炎患者47例，采用薄荷素油胶囊联合多潘立酮治疗，薄荷素油胶囊0．9g，3次／d；多潘立酮10 mg，3次／d；两药连服4周，4周后复查胃镜及病理组织学，观察患者临床症状改善情况和胃镜下炎症及胆汁反流改善情况，评价患者的临床效果。结果治疗后，显效和有效患者共42例，总有效率为89.4％；无效5例，占10．6％。所有患者治疗期间未出现明显不良反应。结论薄荷素油胶囊联合多潘立酮治疗胃手术后胆汁反流性胃炎临床疗效满意，可在临床上推广应用。
목적：관찰박하소유효낭연합다반립동치료위수술후담즙반류성위염적림상료효。방법선택위수술후담즙반류성위염환자47례，채용박하소유효낭연합다반립동치료，박하소유효낭0．9g，3차／d；다반립동10 mg，3차／d；량약련복4주，4주후복사위경급병리조직학，관찰환자림상증상개선정황화위경하염증급담즙반류개선정황，평개환자적림상효과。결과치료후，현효화유효환자공42례，총유효솔위89.4％；무효5례，점10．6％。소유환자치료기간미출현명현불량반응。결론박하소유효낭연합다반립동치료위수술후담즙반류성위염림상료효만의，가재림상상추엄응용。
Objective To observe the clinical efficacy of peppermint oil capsules combined with domperi-done in the treatment of bile reflux gastritis(BRG)after gastric surgery.Methods Totally 47 patients with BRG after gastric surgery were treated with peppermint oil capsule (0.9g,tid)and domperidone(10mg,tid).Each patient's gas-troscopic manifestations and histopathology were rechecked after 4 weeks.The efficacy was observed on the improve-ment of symptoms and gastric mucosal injury,and on the reduction of bile reflux.Results 42 patients attained satis-factory therapeutic effect with the total efficiency rate of 89.4%.No adverse effects during the treatment period. Conclusion Peppermint oil capsules combined with domperidone shows better efficacy in treatment of BRG after gastric surgery.