中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2015年
8期
1204-1206,1207
,共4页
麻醉%地佐辛%瑞芬太尼%胃镜检查%老年人
痳醉%地佐辛%瑞芬太尼%胃鏡檢查%老年人
마취%지좌신%서분태니%위경검사%노년인
Anesthesia%Dezocine%Remifentanil%Gastroscopy%Aged
目的:比较地佐辛与瑞芬太尼在老年人无痛胃镜检查中的应用效果。方法选择行无痛胃镜检查的老年患者180例,采用随机数字表法将患者随机分为地佐辛组(D组)、瑞芬太尼组(R组)和对照组(C组),每组60例。D组患者静脉注射地佐辛20μg/kg;R组患者静脉注射瑞芬太尼0.5μg/kg;C组静脉注射0.9%氯化钠注射液1 mL。在注射1 min后,所有患者静脉注射丙泊酚1 mg/kg进行麻醉诱导。观察各组丙泊酚总用量、起效时间、苏醒时间、离院时间、术中HR、MAP和SpO2变化,苏醒时镇静评分,术后有无恶心、呕吐等并发症。结果 D组患者MAP下降缓和,与其他两组比较差异有统计学意义(tDR =2.278,PDR <0.05;tDC =2.545,PDC <0.05),R组和C组SpO2较D组明显下降(tDR=2.184,PDR<0.05;tDC =2.206,PDC <0.05), D组、R组的苏醒时间较C组明显缩短(tDC =5.401,PDC <0.01;tRC =6.674,PRC <0.01),丙泊酚总用量与C组相比也显著减少(tDC =3.726,PDC <0.01;tRC =4.213,PRC <0.01)。D组患者苏醒时的RSS评分为(2.3±0.7)分,低于C组的(3.8±1.2)分、R组的(3.6±0.9)分(tDC =8.938,PDC <0.01;tDR=7.154,PDR<0.01),检查中不良反应少。结论地佐辛复合丙泊酚较瑞芬太尼复合丙泊酚更适用于老年人无痛胃镜检查,具有麻醉效果确切,呼吸抑制减少,苏醒时清醒程度高,不良反应少等优点。
目的:比較地佐辛與瑞芬太尼在老年人無痛胃鏡檢查中的應用效果。方法選擇行無痛胃鏡檢查的老年患者180例,採用隨機數字錶法將患者隨機分為地佐辛組(D組)、瑞芬太尼組(R組)和對照組(C組),每組60例。D組患者靜脈註射地佐辛20μg/kg;R組患者靜脈註射瑞芬太尼0.5μg/kg;C組靜脈註射0.9%氯化鈉註射液1 mL。在註射1 min後,所有患者靜脈註射丙泊酚1 mg/kg進行痳醉誘導。觀察各組丙泊酚總用量、起效時間、囌醒時間、離院時間、術中HR、MAP和SpO2變化,囌醒時鎮靜評分,術後有無噁心、嘔吐等併髮癥。結果 D組患者MAP下降緩和,與其他兩組比較差異有統計學意義(tDR =2.278,PDR <0.05;tDC =2.545,PDC <0.05),R組和C組SpO2較D組明顯下降(tDR=2.184,PDR<0.05;tDC =2.206,PDC <0.05), D組、R組的囌醒時間較C組明顯縮短(tDC =5.401,PDC <0.01;tRC =6.674,PRC <0.01),丙泊酚總用量與C組相比也顯著減少(tDC =3.726,PDC <0.01;tRC =4.213,PRC <0.01)。D組患者囌醒時的RSS評分為(2.3±0.7)分,低于C組的(3.8±1.2)分、R組的(3.6±0.9)分(tDC =8.938,PDC <0.01;tDR=7.154,PDR<0.01),檢查中不良反應少。結論地佐辛複閤丙泊酚較瑞芬太尼複閤丙泊酚更適用于老年人無痛胃鏡檢查,具有痳醉效果確切,呼吸抑製減少,囌醒時清醒程度高,不良反應少等優點。
목적:비교지좌신여서분태니재노년인무통위경검사중적응용효과。방법선택행무통위경검사적노년환자180례,채용수궤수자표법장환자수궤분위지좌신조(D조)、서분태니조(R조)화대조조(C조),매조60례。D조환자정맥주사지좌신20μg/kg;R조환자정맥주사서분태니0.5μg/kg;C조정맥주사0.9%록화납주사액1 mL。재주사1 min후,소유환자정맥주사병박분1 mg/kg진행마취유도。관찰각조병박분총용량、기효시간、소성시간、리원시간、술중HR、MAP화SpO2변화,소성시진정평분,술후유무악심、구토등병발증。결과 D조환자MAP하강완화,여기타량조비교차이유통계학의의(tDR =2.278,PDR <0.05;tDC =2.545,PDC <0.05),R조화C조SpO2교D조명현하강(tDR=2.184,PDR<0.05;tDC =2.206,PDC <0.05), D조、R조적소성시간교C조명현축단(tDC =5.401,PDC <0.01;tRC =6.674,PRC <0.01),병박분총용량여C조상비야현저감소(tDC =3.726,PDC <0.01;tRC =4.213,PRC <0.01)。D조환자소성시적RSS평분위(2.3±0.7)분,저우C조적(3.8±1.2)분、R조적(3.6±0.9)분(tDC =8.938,PDC <0.01;tDR=7.154,PDR<0.01),검사중불량반응소。결론지좌신복합병박분교서분태니복합병박분경괄용우노년인무통위경검사,구유마취효과학절,호흡억제감소,소성시청성정도고,불량반응소등우점。
Objective To investigate the clinical application of dezocine and remifentanil in elderly patients with painless gastroscopy.Methods According to random number table,180 elderly patients undergoing painless gas-troscopy were randomly divided into dezocine group(group D),remifentanil group(group R)and control group(group C),each group 60 cases.Group D was infusion with dezocine 20μg/kg,Group R was infusion with remifentanil 0.5μg/kg and Group C was infused with normal saline,then three groups patients,respectively,after the interval of 1 minutes were given propofol 1 mg/kg.Objects induced sum of propofol,starting time,awakening time,discharged time,HR,MAP and SpO2 during operation,sedation scores,postoperative side effects such as nausea and vomiting were observed.Results The decrease of MAP was alleviated in group D compared with group C and group S(tDR =2.278,PDR<0.05 and tDC =2.545,PDC <0.05).SpO2 in group C and group R were significantly lower than that in group D(tDR=2.184,PDR<0.05 and tDC =2.206,PDC <0.05).The time for regaining consciousness(tDC =5.401 and tRC =6.674)and propofol dosage(tDC =3.726 and tRC=4.213)in group D and group R were significantly lower than those in group C(P<0.05).The Ramsay of group D was (2.3 ±0.7)points,which was lower than (3.8 ±1.2) points of group C,(3.6 ±0.9)points of group R(tDC =8.938,PDC <0.01;tDR=7.154,PDR<0.01),and there were fewer adverse reactions in group D.Conclusion Dezocine is more suitable for the elderly patients than remifentanil, which has exact effect of anesthesia,less respiratory depression,higher level of consciousness awakening and fewer adverse reactions.