CAJ | 학술논문

目的：探讨广西地区不同民族食管癌患者手术前后免疫功能状态。方法利用酶联免疫吸附法检测123例食管癌患者手术前后外周血白细胞介素2（IL‐2）、白细胞介素6（IL‐6）、白细胞介素10（IL‐10）及白细胞介素23（IL‐23）水平。结果手术前IL‐2水平在汉族、壮族、苗族、瑶族食管癌患者之间比较，差异有统计学意义（P＜0．05），IL‐6、IL‐10、IL‐23水平在不同民族患者之间差异无统计学意义（ P＞0．05）；手术后IL‐2、IL‐6、IL‐10、IL‐23水平在汉族、壮族、苗族、瑶族食管癌患者中差异无统计学意义（ P＞0．05）；手术前后IL‐2、IL‐23水平比较，汉族患者术前均高于术后，壮族患者IL‐23水平术前高于术后（ P＜0．05）。结论广西地区汉族、壮族、苗族、瑶族食管癌患者免疫功能状态存在一定差异，手术对汉族及壮族食管癌患者的免疫功能影响较大，而对苗族及瑶族患者无影响。
목적：탐토엄서지구불동민족식관암환자수술전후면역공능상태。방법이용매련면역흡부법검측123례식관암환자수술전후외주혈백세포개소2（IL‐2）、백세포개소6（IL‐6）、백세포개소10（IL‐10）급백세포개소23（IL‐23）수평。결과수술전IL‐2수평재한족、장족、묘족、요족식관암환자지간비교，차이유통계학의의（P＜0．05），IL‐6、IL‐10、IL‐23수평재불동민족환자지간차이무통계학의의（ P＞0．05）；수술후IL‐2、IL‐6、IL‐10、IL‐23수평재한족、장족、묘족、요족식관암환자중차이무통계학의의（ P＞0．05）；수술전후IL‐2、IL‐23수평비교，한족환자술전균고우술후，장족환자IL‐23수평술전고우술후（ P＜0．05）。결론엄서지구한족、장족、묘족、요족식관암환자면역공능상태존재일정차이，수술대한족급장족식관암환자적면역공능영향교대，이대묘족급요족환자무영향。
Objective To explore the influence of immune function about operation treatments for patients with esophageal carcinoma(EC) in Guangxi different nationalities .Methods Whole blood and serum of 123 cases were respectively collected in EC patients before and after radical resection of esophageal carcinoma;the content of IL‐2 ,IL‐6 ,IL‐10 and IL‐23 were detected;the differences of the immune index among different ethnic groups or in the same nation before and after radiation treatments were statistically analyzed .Results IL‐2 was significant different in the different nationalitily patients before radical resection of esophageal carcinoma;the level of IL‐2 was significant differences between Han patients after radical resection of EC ;the level of IL‐23 was significant differences between Zhuang and Han patients after radical resection of EC(P< 0 .05) .Conclusion The body′s immune function exist differences in different nationalities of esophageal patients .And radical resection of esophageal carcinoma for patients immune function had different impact among four nationalities .