CAJ | 학술논문

目的：调查南充市Rh阴性无偿献血者的血清学表型和不规则抗体情况。方法应用血型血清学方法对初检Rh阴性的献血者进行Rh阴性确认、血清学表型鉴定及不规则抗体筛选鉴定。结果在433份送检标本中共确认Rh阴性402份（92．8％），检出D变异体23份（5．3％），其余8份（1．9％）为检验科RhD检测错误；共检出不规则抗体12份，在Rh确认阴性献血者中检出7份抗‐D （1．7％）；Rh阴性献血者的血清学表型分布结果主要以dccee和dCcee为主，其余为dCCee、dccEe和dCcEe。结论通过本次调查，掌握了南充市Rh阴性无偿献血者的血清学表型和不规则抗体的分布情况，保障了临床Rh阴性患者输血安全性、有效性和及时性。
목적：조사남충시Rh음성무상헌혈자적혈청학표형화불규칙항체정황。방법응용혈형혈청학방법대초검Rh음성적헌혈자진행Rh음성학인、혈청학표형감정급불규칙항체사선감정。결과재433빈송검표본중공학인Rh음성402빈（92．8％），검출D변이체23빈（5．3％），기여8빈（1．9％）위검험과RhD검측착오；공검출불규칙항체12빈，재Rh학인음성헌혈자중검출7빈항‐D （1．7％）；Rh음성헌혈자적혈청학표형분포결과주요이dccee화dCcee위주，기여위dCCee、dccEe화dCcEe。결론통과본차조사，장악료남충시Rh음성무상헌혈자적혈청학표형화불규칙항체적분포정황，보장료림상Rh음성환자수혈안전성、유효성화급시성。
Objective To investigate the serological phenotype and irregular antibody of Rh negative blood do‐nors in Nanchong .Methods Blood group serology was used to reconfirm Rh negative、to screen and identify the sero‐logical phenotype and irregular antibody for Rh negative blood donors in primary detectionResults Among 433 speci‐mens ,a total of 402 cases(92 .8% ) were confirmed as Rh negative ,23 cases were D variants(5 .3% ) ,and the rest 8 cases were check errors(1 .9% );Irregular antibodies were found in 12 cases ,and 7 cases of anti‐D(1 .7% ) in recon‐firmed Rh negative blood donor ;The serological phenotype of Rh negative blood donor was given priority to dccee and dCcee ,followed by dCCee ,dccEe and dCcEe .Conclusion The serological phenotype of the Rh negative blood donors in our region Characterized by diversity ,there was irregular antibodies in Rh negative blood donors .