CAJ | 학술논문

目的：探讨肠球菌属细菌分布及耐药性特征，为指导临床合理用药及控制医院感染提供依据。方法对该院2011年1月至2013年12月年临床送检标本进行细菌分离培养、鉴定和药敏试验。结果共检出肠球菌属细菌140株，屎肠球菌71株（50．7％），粪肠球菌60株（42．9％），其他肠球菌9株（6．4％），其中尿液99株（70．7％）；粪肠球菌对青霉素、氨苄西林、红霉素的耐药率为15．0％、12．5％和75．0％，屎肠球菌对青霉素、氨苄西林、左氧氟沙星、环丙沙星、红霉素耐药率大于80．0％，粪肠球菌和屎肠球菌对万古霉素（5．0％、4．2％）、利奈唑胺（8．4％、1．4％）极度敏感，喹奴普丁／达福普丁对粪肠球菌耐药率（100．0％）高于屎肠球菌（26．7％），达托霉素无耐药菌株。结论肠球菌属以泌尿系统感染为主，屎肠球菌检出率略大于粪肠球菌，屎肠球菌对大多数抗菌药物耐药率高于粪肠球菌，喹奴普丁／达福普丁仅对屎肠球菌有较高敏感性，万古霉素、利奈唑胺、达托霉素对肠球菌属细菌保持极高敏感性。
목적：탐토장구균속세균분포급내약성특정，위지도림상합리용약급공제의원감염제공의거。방법대해원2011년1월지2013년12월년림상송검표본진행세균분리배양、감정화약민시험。결과공검출장구균속세균140주，시장구균71주（50．7％），분장구균60주（42．9％），기타장구균9주（6．4％），기중뇨액99주（70．7％）；분장구균대청매소、안변서림、홍매소적내약솔위15．0％、12．5％화75．0％，시장구균대청매소、안변서림、좌양불사성、배병사성、홍매소내약솔대우80．0％，분장구균화시장구균대만고매소（5．0％、4．2％）、리내서알（8．4％、1．4％）겁도민감，규노보정／체복보정대분장구균내약솔（100．0％）고우시장구균（26．7％），체탁매소무내약균주。결론장구균속이비뇨계통감염위주，시장구균검출솔략대우분장구균，시장구균대대다수항균약물내약솔고우분장구균，규노보정／체복보정부대시장구균유교고민감성，만고매소、리내서알、체탁매소대장구균속세균보지겁고민감성。
Objective To explore the distribution and resistance characteristics of enteroco‐ccus bacteria and offer guidance for rational administration and nosocomial infection .Methods Clinical specimens in our hospital from Jan 2011 to Dec 2013 were cultivated ,then the identification and drug sensitivity test were carried out .Results 140 strains of enterococcus were detected ,in which 99 strains (70 .7% )were from urine;Excrement enterococcus 71 strains (50 .7% ) ,60 in enterococcus strains (42 .9% ) ,9 other enterococcus strains(6 .4% );the drug of resistance rate of E .faecium to penicillin was 15 .0% ,ampicillin 12 .5% ,erythromycin 75 .0% ;while the drug of resistance rates of E .faecalis to penicillin ,ampicillin ,levofloxacin ,ciprofloxacin and erythromycin were more than 80 .0% ;E .faecium and E .faecalis were acutely sensitive to vancomycin and linezolid ,the drug of resistance rates of E .faecium and E . faecalis to vancomycin were 5 .0% ,4 .2% respectively ,linezolid were 8 .4% ,1 .4% respectively ,the drug of resistance rate of E .faecium to quinupristin/dalfopristin(100 .0% ) was more than E .faecalis(26 .7% ) ,resistant strains of dap‐tomycin have not been found so far .Conclusion Enterococcus was the predominant specie causing urinary tract infec‐tions ,and the detection rate of E .faecalis slightly greater than E .faecium ,the majority resistance to antimicrobial a‐gents of E .faecalis were more than E .faecium ;quinupristin、dalfopristin only has a higher sensitivity to E .faecalis;at the same time ,vancomycin ,linezolid and daptomycin keep high sensitivity to enterococcus .