CAJ | 학술논문

目的：观察不同灸法对环磷酰胺所致免疫抑制兔外周血细胞的影响。方法：大耳白兔50只随机分为5组，分别为空白组、模型组、隔药饼灸组、艾灸组、假药饼灸组。除空白组外均腹腔注射环磷酰胺60 mg/kg，连续7 d，造成免疫抑制模型。3个治疗组分别进行隔药饼灸、艾灸、假药饼灸治疗，隔日灸，共灸10次。灸疗结束次日静脉取血，进行血细胞系列的检测。结果：与空白组比较，模型组WBC、NEU、RBC、HGB、HCT均显著降低（P＜0.01）。与模型组比较，隔药饼灸组WBC、NEU、RBC、HGB、HCT均升高，差异有统计学意义（P＜0.01）；艾灸组RBC明显升高（P＜0.01）；假药饼灸组9项指标差异均无统计学意义（P＞0.05）。结论：隔药饼灸对因环磷酰胺所致的免疫功能低下状态具有明显的改善作用。
목적：관찰불동구법대배린선알소치면역억제토외주혈세포적영향。방법：대이백토50지수궤분위5조，분별위공백조、모형조、격약병구조、애구조、가약병구조。제공백조외균복강주사배린선알60 mg/kg，련속7 d，조성면역억제모형。3개치료조분별진행격약병구、애구、가약병구치료，격일구，공구10차。구료결속차일정맥취혈，진행혈세포계렬적검측。결과：여공백조비교，모형조WBC、NEU、RBC、HGB、HCT균현저강저（P＜0.01）。여모형조비교，격약병구조WBC、NEU、RBC、HGB、HCT균승고，차이유통계학의의（P＜0.01）；애구조RBC명현승고（P＜0.01）；가약병구조9항지표차이균무통계학의의（P＞0.05）。결론：격약병구대인배린선알소치적면역공능저하상태구유명현적개선작용。
Objective:To observe the influence of blood cells series in immunosuppressive rabbits treated with herbal cake-separated moxibustion,moxibustion and sham cake-separated moxibustion. Methods:50 rabbits were randomly di-vided into blank group,model group,herbal cake-separated moxibustion group,moxibustion group and sham cake-sepa-rated moxibustion group. Except the blank group,other groups were given intraperitoneal injection of cyclophosphamide (Cy)60 mg/kg in 7 consecutive days so as to set up the immunosuppressive model. Three treatment groups were treated every other day by herbal cake-separated moxibustion,moxibustion,sham cake-separated moxibustion respectively,a total of 10 times. Then abdominal vein blood was collected and blood cell series was detected after treatment. Results:Com-pared with the blank group,the WBC、NEU、RBC、HGB、HCT of model group were significantly decreased(P<0.01). Com-pared with model group,the WBC,RBC,HGB,HCT,NEU of herbal cake-separated moxibustion group were extremely sig-nificant increased (P<0.01). The RBC of moxibustion group was significantly higher than that of model gronp (P<0.01). Conclusion:Herbal cake-separated moxibustion has obvious effect on improving immunosuppressive state of rabbits in-duced by cyclophosphamide.