CAJ | 학술논문

目的：对遗忘型轻度认知障碍的CT表现及临床演变进行了研究。方法从我院2011年12月-2014年6月收治的aMCI病例选取45人，筛选认知检查、同期记忆都无异常的54-76岁健康人群38人为健康对照组，全部自愿配合检查和量表评估。采用中国医学科学院心理研究所许淑莲主编的临床记忆量表。运用CT检测外侧裂宽度、海马回钩间距、额角指数及颞角宽度。以海马回钩间距／大脑横径的比值计算出海马指数。分析CT用于遗忘型轻度认知障碍和正常组之间的灵敏性和特异性。结果：遗忘型轻度认知障碍患者45例和健康者38人全部进入结果分析。 aMCI病例组记忆等值量表评分结果及记忆商低于健康对照组(p<0.01)。脑CT的结果如下， aMCI病例组海马指数和外侧裂宽度均高于健康对照组(p<0.05)。结论遗忘型轻度认知障碍患者脑CT变化，为临床诊治提供了客观的指标，并实现对MCI老年患者的早期筛查，早期预防，为aMCI的一级预防提供有益的信息。
목적：대유망형경도인지장애적CT표현급림상연변진행료연구。방법종아원2011년12월-2014년6월수치적aMCI병례선취45인，사선인지검사、동기기억도무이상적54-76세건강인군38인위건강대조조，전부자원배합검사화량표평고。채용중국의학과학원심리연구소허숙련주편적림상기억량표。운용CT검측외측렬관도、해마회구간거、액각지수급섭각관도。이해마회구간거／대뇌횡경적비치계산출해마지수。분석CT용우유망형경도인지장애화정상조지간적령민성화특이성。결과：유망형경도인지장애환자45례화건강자38인전부진입결과분석。 aMCI병례조기억등치량표평분결과급기억상저우건강대조조(p<0.01)。뇌CT적결과여하， aMCI병례조해마지수화외측렬관도균고우건강대조조(p<0.05)。결론유망형경도인지장애환자뇌CT변화，위림상진치제공료객관적지표，병실현대MCI노년환자적조기사사，조기예방，위aMCI적일급예방제공유익적신식。
clinical development and CT manifestations of amnestic mild cognitive impairment were studied. selected 45 patients from aMCI cases between December 2011 and June 2014 from the Third People’s Hospital of Foshan, then chose 3 54-76 years old people that were healthy in cognitive check and memory as the control group to participate in the voluntary inspection and assessment. Using the clinical memory scale edited by XU Shu-lian from Psychology Institute of Chinese Academy of Medical Sciences; using CT to detect the width of lateral fissure, hippocampus hook spacing, frontal horn index and width of temporal horn. Calculated the hippocampus index at the ratio of he hippocampal hook spacing to cereb r al transverse diameter. Analyzed the sensitivity and specificity of CT hetween mild cognitive impairment and normal groups. 45 amnestic mild cognitive impairment and 3 healthy subjects were involved in the result analysis. Both memory equivalent scale score results and memory quotient of aMCI cases were lower than control group (p<0.01 . Brain CT results were as follow, both hippocampal index and lateral fissure width of aMCI cases were higher than control group (p<0.05 . brain CT changes of patients with amnestic mild cognitive impairment provide objective indicator for clinical diagnosis and treatment, make early screening and early prevention possible for aged aMCI patients, and are helpful to provide useful information for primary prevention of senile dementia.