CAJ | 학술논문

手性醇是合成医药、农用化学品和其他精细化学品的关键中间体。硫酸酯酶可催化水解硫酸酯键裂解形成无机硫酸盐和相应的仲醇。笔者综述了硫酸酯酶微生物来源、催化反应机制及其应用，也介绍了固定化提高催化稳定性及通过添加金属离子或有机助溶剂提高硫酸酯酶选择性的方法。
수성순시합성의약、농용화학품화기타정세화학품적관건중간체。류산지매가최화수해류산지건렬해형성무궤류산염화상응적중순。필자종술료류산지매미생물래원、최화반응궤제급기응용，야개소료고정화제고최화은정성급통과첨가금속리자혹유궤조용제제고류산지매선택성적방법。
Chiral alcohols are key intermediates in the synthesis of pharmaceutical, agrochemical, and other fine chemicals. Sulfatase can catalyze the hydrolytic cleavage of sulfate esters by liberating inorganic sulfate and the corresponding secondary alcohol. In this review,microbial sources,catalytic mechanisms, and applications of sulfatase were summarized. Moreover, methods for improving catalytic stability by immobilization and enhancing selectivity by addition of metal ions or organic cosolvents were introduced.