CAJ | 학술논문

目的：探讨无痛胃镜下美蓝染色后胃黏膜切除（EMR）病理活检对早期胃癌及癌前病变的诊断价值。方法：将我院无痛胃镜检查发现胃黏膜色泽异常、粗糙不平、轻微隆起、浅凹陷等异常改变者120例随机分为两组，即实验组与对照组，各60例。实验组胃黏膜喷洒0.5%美蓝溶液，并行EMR切除可疑病灶组织，病理检查；对照组不染色，只用活检钳常规病理活检。对比两组早期胃癌及不典型增生、肠上皮化生的检出率，并进行统计学分析。结果：实验组早期胃癌检出率11.7%（7/60），不典型增生和肠上皮化生73.3%（44/60）；对照组分别为3.3%（2/60）及31.7（19/60）。实验组早期胃癌及不典型增生、肠上皮化生检出率均显著高于对照组，两组差异有统计学意义（<0.05）。结论：无痛胃镜下美篮染色结合EMR可显著提高早期胃癌及癌前病变的检出率。
목적：탐토무통위경하미람염색후위점막절제（EMR）병리활검대조기위암급암전병변적진단개치。방법：장아원무통위경검사발현위점막색택이상、조조불평、경미륭기、천요함등이상개변자120례수궤분위량조，즉실험조여대조조，각60례。실험조위점막분쇄0.5%미람용액，병행EMR절제가의병조조직，병리검사；대조조불염색，지용활검겸상규병리활검。대비량조조기위암급불전형증생、장상피화생적검출솔，병진행통계학분석。결과：실험조조기위암검출솔11.7%（7/60），불전형증생화장상피화생73.3%（44/60）；대조조분별위3.3%（2/60）급31.7（19/60）。실험조조기위암급불전형증생、장상피화생검출솔균현저고우대조조，량조차이유통계학의의（<0.05）。결론：무통위경하미람염색결합EMR가현저제고조기위암급암전병변적검출솔。
Objective: Tunder painless gastroscopy in methylene blue staining in gastric mucosa resection ( EMR) Biopsy in the diagnosis of early gastric carcinoma and precancerous lesions. Methods:will be our gastric mucosa of painless gastroscopy examination revealed abnormal color, rough, slightly elevated, shallow depressions and other abnormalities in 120 patients were randomly divided into two groups, the experimental group and the control group, in 60 cases. Gastric mucosa of experimental group 0, 5%, methylene blue solution sprayed, parallel organization EMR excision suspicious lesion, pathologic examination; No staining in the control group, only use biopsy forceps conventional biopsy. Results:comparing two groups of early gastric cancer and atypical hyperplasia, the detection rate of intestinal metaplasia, and for statistical analysis. 11. 7% results of early gastric cancer detection rate (7/60) , atypical hyperplasia, and intestinal metaplasia 73. 3% (44/60) ; Control group were 3. 3% (2/60) and 31. 7 per cent (19/60) . Experimental group, intestinal metaplasia, early gastric cancer and atypical hyperplasia de-tection rates are significantly higher than those in the control group, there was a significant difference between the two groups (P<0. 05) . Conclusions:under painless gastroscopy in the US basket dye to EMR can significantly improve the detection rate of early gastric cancer and precancerous lesions.