CAJ | 학술논문

目的：通过对临床肿瘤Ⅲ～Ⅳ期患者QLQ-C30生活量表与对照组比较来观察施用麦粒灸治疗后两组不同中医证型患者生活质量的不同及其 IL-10表达的差异，以此来探寻在肿瘤Ⅲ～Ⅳ期治疗中麦粒灸的治疗是否能改善患者的生活质量，调节肿瘤相关免疫，提高带瘤生存率。方法将42例肿瘤患者随机分为治疗组和对照组，并进行中医辨证分型，治疗组在常规中西医结合治疗的基础上加用2星期麦粒灸治疗，对两组患者治疗前及治疗后分别进行QLQ-C30生活量表评分，并留取外周血标本进行IL-10检测。结果麦粒灸治疗能改善患者生活质量，尤其以乏力及纳差改善明显；麦粒灸治疗后IL-10的表达较治疗前有所下降。结论麦粒灸能改善肿瘤患者生存质量，下调IL-10的表达。
목적：통과대림상종류Ⅲ～Ⅳ기환자QLQ-C30생활량표여대조조비교래관찰시용맥립구치료후량조불동중의증형환자생활질량적불동급기 IL-10표체적차이，이차래탐심재종류Ⅲ～Ⅳ기치료중맥립구적치료시부능개선환자적생활질량，조절종류상관면역，제고대류생존솔。방법장42례종류환자수궤분위치료조화대조조，병진행중의변증분형，치료조재상규중서의결합치료적기출상가용2성기맥립구치료，대량조환자치료전급치료후분별진행QLQ-C30생활량표평분，병류취외주혈표본진행IL-10검측。결과맥립구치료능개선환자생활질량，우기이핍력급납차개선명현；맥립구치료후IL-10적표체교치료전유소하강。결론맥립구능개선종류환자생존질량，하조IL-10적표체。
ObjectiveBy observing and comparing the effect of wheat-sized moxibustion on the quality of life and interleukin (IL)-10 expression in stageⅢ~Ⅳtumor patients of two different traditional Chinese medicine (TCM) patterns by using QLQ-C30 questionnaire, to see whether wheat-sized moxibustion can improve the quality of life, regulate oncology-related immune system, and enhance the survival rate of the stageⅢ~Ⅳtumor patients.MethodForty-two tumor patients were randomized into a treatment group and a control group and were differentiated into TCM patterns. The treatment group was intervened by conventional Chinese and Western medicine plus 2 weeks of wheat-sized moxibustion. QLQ-C30 questionnaire was adopted for evaluation before and after treatment, and peripheral blood was drawn to detect the expression of IL-10.ResultWheat-sized moxibustion improved the quality of life, especially fatigueand poor appetite; the expression of IL-10 dropped after wheat-sized moxibustion.Conclusion Wheat-sized moxibustion can improve the quality of life of the tumor patients and down-regulate the expression of IL-10.