中国当代儿科杂志
中國噹代兒科雜誌
중국당대인과잡지
CHINA JOURNAL OF CONTEMPORARY PEDIATRICS
2015年
4期
414-419
,共6页
奥卡西平%癫癎%不良反应
奧卡西平%癲癎%不良反應
오잡서평%전간%불량반응
Oxcarbazepine%Epilepsy%Adverse effect
奥卡西平（oxcarbazepine, OXC）是一种新型抗癫癎药物，由于其耐受性好，药物间的相互作用少，在临床得到越来越广泛的应用，但其毒副作用仍不可忽视。OXC的不良反应以中枢神经系统和消化系统多见，如：疲劳、嗜睡、复视、头晕、恶心、呕吐等；皮肤不良反应主要为皮疹；长期服用OXC还可能引起低钠血症。本文搜集国内外近十年有关OXC不良反应的文献，并对其进行归纳分析，旨在为OXC的临床合理用药提供参考。
奧卡西平（oxcarbazepine, OXC）是一種新型抗癲癎藥物，由于其耐受性好，藥物間的相互作用少，在臨床得到越來越廣汎的應用，但其毒副作用仍不可忽視。OXC的不良反應以中樞神經繫統和消化繫統多見，如：疲勞、嗜睡、複視、頭暈、噁心、嘔吐等；皮膚不良反應主要為皮疹；長期服用OXC還可能引起低鈉血癥。本文搜集國內外近十年有關OXC不良反應的文獻，併對其進行歸納分析，旨在為OXC的臨床閤理用藥提供參攷。
오잡서평（oxcarbazepine, OXC）시일충신형항전간약물，유우기내수성호，약물간적상호작용소，재림상득도월래월엄범적응용，단기독부작용잉불가홀시。OXC적불량반응이중추신경계통화소화계통다견，여：피로、기수、복시、두훈、악심、구토등；피부불량반응주요위피진；장기복용OXC환가능인기저납혈증。본문수집국내외근십년유관OXC불량반응적문헌，병대기진행귀납분석，지재위OXC적림상합리용약제공삼고。
Oxcarbazepine is a new antiepileptic drug. The results of clinical trials suggest that oxcarbazepine is well tolerated and has less drug interactions. It is being used more and more widely in clinical practice, but its adverse effects should not be ignored. The most common adverse effects of oxcarbazepine are usually related to the central nervous system and digestive system, including fatigue, drowsiness, diplopia, dizziness, nausea and vomit. The common skin adverse reaction is rash. Long-term use of oxcarbazepine may also cause hyponatremia. This article reviews the literature from China and overseas about the adverse effets of oxcarbazepine over the last 10 years in order to ifnd information about rational clinical use of oxcarbazepine.
