CAJ | 학술논문

目的：探讨肌钙蛋白(cTnI)、降钙素原(PCT)对心脏术后感染性休克病情程度的预测价值。方法根据是否合并感染性休克将我院重症监护室的106例心脏术后患者分为观察组(合并感染性休克，50例)和对照组(未合并感染性休克，56例)。采用免疫吸附试验法检测cTnI水平，免疫散射比浊法检测PCT水平，比较两组患者的cTnI和PCT水平。结果观察组cTnI和PCT水平分别为(5.64±1.05)μg/L和(1.95±0.31) ng/L，高于对照组的(0.72±3.12)μg/L和(0.28±0.15) ng/L，差异具有统计学意义(P<0.05)。感染性休克患者开始发病时的cTnI和PCT水平均明显高于治疗12 h和治疗24 h时，而且随着治疗时间的延长， cTnI和PCT水平也降低，差异均具有统计学意义(P<0.05)。结论肌钙蛋白和降钙素原对心脏术后感染性休克具有重要的诊断意义，对不同病情程度的感染性休克具有预测作用。
목적：탐토기개단백(cTnI)、강개소원(PCT)대심장술후감염성휴극병정정도적예측개치。방법근거시부합병감염성휴극장아원중증감호실적106례심장술후환자분위관찰조(합병감염성휴극，50례)화대조조(미합병감염성휴극，56례)。채용면역흡부시험법검측cTnI수평，면역산사비탁법검측PCT수평，비교량조환자적cTnI화PCT수평。결과관찰조cTnI화PCT수평분별위(5.64±1.05)μg/L화(1.95±0.31) ng/L，고우대조조적(0.72±3.12)μg/L화(0.28±0.15) ng/L，차이구유통계학의의(P<0.05)。감염성휴극환자개시발병시적cTnI화PCT수평균명현고우치료12 h화치료24 h시，이차수착치료시간적연장， cTnI화PCT수평야강저，차이균구유통계학의의(P<0.05)。결론기개단백화강개소원대심장술후감염성휴극구유중요적진단의의，대불동병정정도적감염성휴극구유예측작용。
Objective To study the predictive value of cardiac troponin (cTnI) and procalcitonin (PCT) in the illness degree of infectious shock after cardiac surgery. Methods 106 cases of patients after cardiac surgery in ICU were divided into observation group (complicating infectious shock, 50 cases) and control group (without infection, 56 cases) according to whether complicating infectious shock. The level of cTnI was detected by ELISA, the level of PCT was detected by immune nephelometry. The cTnI and PCT levels of two groups were compared. Results The level of cTnI and PCT in observation group were (5.64 ± 1.05) μg/L and (1.95 ± 0.31) ng/L respectively, higher than (0.72±3.12)μg/L and (0.28±0.15) ng/L in control group, with statistical difference (P<0.05). The level of cTnI and PCT of infectious shock patients at onset were higher than the level after 12 h and 24 h of treatment, and with the extension of treatment time, the cTnI and PCT were decreased, all the difference was statistical (P <0.05). Conclusions cTnI and PCT have important diagnostic significance in infectious shock after cardiac surgery, and have predictive value in different illness degree of infectious shock.