CAJ | 학술논문

目的：探讨输血对贫血早产儿生命体征及心脏功能的影响。方法采用前瞻性队列研究方法，以胎龄<34周、出生1周后接受输血治疗的40例贫血早产儿为研究对象。运用便携式超声诊断仪测定输血前与输血结束后24 h内左心室射血分数、短轴缩短率、每搏输出量、心输出量。输血前后各24 h内记录患儿有无呼吸暂停及呼吸暂停次数；输血前及输血结束时，在患儿安静时监测一次体温、血压，同时输血前后各4 h内每小时记录一次患儿安静时的心率、呼吸频率、经皮氧饱和度等。结果与输血前比较，输血后4 h内患儿心率、呼吸频率均明显下降（P<0.05）。4例患儿输血前24 h内有呼吸暂停，输血后24 h内未再出现呼吸暂停。输血后收缩压、舒张压、平均动脉压、体温较前均无显著变化（P>0.05）；输血后左心室射血分数、每搏输出量、心输出量、短轴缩短率较前均无显著变化（P>0.05）。结论输血可以改善贫血早产儿的临床症状，而且对心脏功能无显著影响。
목적：탐토수혈대빈혈조산인생명체정급심장공능적영향。방법채용전첨성대렬연구방법，이태령<34주、출생1주후접수수혈치료적40례빈혈조산인위연구대상。운용편휴식초성진단의측정수혈전여수혈결속후24 h내좌심실사혈분수、단축축단솔、매박수출량、심수출량。수혈전후각24 h내기록환인유무호흡잠정급호흡잠정차수；수혈전급수혈결속시，재환인안정시감측일차체온、혈압，동시수혈전후각4 h내매소시기록일차환인안정시적심솔、호흡빈솔、경피양포화도등。결과여수혈전비교，수혈후4 h내환인심솔、호흡빈솔균명현하강（P<0.05）。4례환인수혈전24 h내유호흡잠정，수혈후24 h내미재출현호흡잠정。수혈후수축압、서장압、평균동맥압、체온교전균무현저변화（P>0.05）；수혈후좌심실사혈분수、매박수출량、심수출량、단축축단솔교전균무현저변화（P>0.05）。결론수혈가이개선빈혈조산인적림상증상，이차대심장공능무현저영향。
ObjectiveTo explore the effects of blood transfusion on the vital signs and heart function in preterm infants with anemia.MethodsA total of 40 anemic preterm infants with gestational age less than 34 weeks who accepted blood transfusion one week after birth were enrolled for a prospective cohort study. Left ventricular ejection fraction (LVEF), fractional shortening (FS), stroke volume (SV), and cardiac output (CO) were determined with portable ultrasonic equipment before blood transfusion and within 24 hours after blood transfusion. Apnea was detected and the times of apnea were recorded within 24 hours before and after blood transfusion. The resting body temperature and blood pressure were also determined before and after blood transfusion. Additionally the resting heart rate, respiratory rate, and transcutaneous oxygen saturation were recorded within 4 hours before and after blood transfusion.Results The heart rate and respiratory rate decreased signiifcantly within 4 hours after blood transfusion (P<0.05). Four infants had apnea within 24 hours before blood transfusion, and nobody had apnea within 24 hours after blood transfusion. The systolic pressure, diastolic pressure, mean arterial pressure, and body temperature showed no signiifcant changes after blood transfusion (P>0.05), and the LVEF, SV, CO, and FS showed no signiifcant changes after blood transfusion as well (P>0.05).ConclusionsBlood transfusion can improve the clinical symptoms and shows no signiifcant effect on the heart function in preterm infants with anemia.