CAJ | 학술논문

目的：评价儿童不同类型冠状动脉瘘（CAF）介入封堵治疗的近中期疗效、并发症及抗凝治疗方案。方法回顾性分析2006年1月至2014年1月行CAF介入封堵治疗的12例患儿术前、造影及术后随访资料，记录不同类型CAF的封堵方式、抗凝方案、术后并发症、辅助检查结果。结果本组患儿年龄1~158个月；近端型/中型4例，近端型/大型5例，远端型/中型3例，均成功封堵；术后随访3.5±2.4年；11例患儿术后口服阿司匹林6个月，1例口服18个月；无血栓、介入并发症，术后左心室射血分数、心胸比、肺动脉压下降，病变冠状动脉开口直径减小。结论儿童期介入封堵治疗近端型和远端型/中型CAF近中期疗效、安全性满意；术后阿司匹林抗凝治疗可预防近中期血栓事件，但疗程和安全性有待进一步随访研究。
목적：평개인동불동류형관상동맥루（CAF）개입봉도치료적근중기료효、병발증급항응치료방안。방법회고성분석2006년1월지2014년1월행CAF개입봉도치료적12례환인술전、조영급술후수방자료，기록불동류형CAF적봉도방식、항응방안、술후병발증、보조검사결과。결과본조환인년령1~158개월；근단형/중형4례，근단형/대형5례，원단형/중형3례，균성공봉도；술후수방3.5±2.4년；11례환인술후구복아사필림6개월，1례구복18개월；무혈전、개입병발증，술후좌심실사혈분수、심흉비、폐동맥압하강，병변관상동맥개구직경감소。결론인동기개입봉도치료근단형화원단형/중형CAF근중기료효、안전성만의；술후아사필림항응치료가예방근중기혈전사건，단료정화안전성유대진일보수방연구。
ObjectiveTo evaluate the short- and medium-term efficacy, complications, and anti-coagulation therapies related to transcatheter closure (TCC) of coronary artery ifstula (CAF) in children.MethodsWe conducted a retrospective review of the medical records of 12 children with CAF who underwent TCC between January 2006 and January 2014, focusing on details such as preoperative, radiographic, and postoperative follow-up data, to record closure methods for CAF, anti-coagulation therapies, postoperative complications, and results of auxiliary examinations. ResultsAmong the 12 cases who underwent successful TCC and whose age was 1-158 months, four patients had proximal/medium-sized CAF, ifve had proximal/large CAF, and three had distal/medium-sized CAF. The mean period of postoperative follow-up was 3.5±2.4 years. Eleven patients took aspirin for 6 months post closure, and one took it for 18 months. Neither coronary thrombosis nor interventional complications were found. Left ventricular ejection fraction, cardiothoracic ratio, pulmonary artery pressure, and the diameters of coronary artery lesions decreased post TCC.ConclusionsTCC is feasible and safe in proximal and distal/medium-sized CAF patients. Postoperative anti-coagulation with aspirin may prevent short- and medium-term thrombosis, but treatment course and safety need to be investigated by further follow-ups.