CAJ | 학술논문

异戊烯基和香叶基结构单元普遍存在于黄酮类、查尔酮类等天然产物。异戊烯基和香叶基结构的查尔酮具有抗癌、抗氧化活性等生理活性而备受青睐。国内外报道了许多异戊烯基和香叶基结构的查尔酮合成方法。本文从苯乙酮或查尔酮为原料基础的两个研究方向进行总结，综述了近年来关于3′，5′位为异戊烯基或香叶基的查尔酮的合成方法，为更多3′，5′位为异戊烯基或香叶基的查尔酮的合成新方法被研发提供参考。
이무희기화향협기결구단원보편존재우황동류、사이동류등천연산물。이무희기화향협기결구적사이동구유항암、항양화활성등생리활성이비수청래。국내외보도료허다이무희기화향협기결구적사이동합성방법。본문종분을동혹사이동위원료기출적량개연구방향진행총결，종술료근년래관우3′，5′위위이무희기혹향협기적사이동적합성방법，위경다3′，5′위위이무희기혹향협기적사이동적합성신방법피연발제공삼고。
Isopentenyl and geranyl structure units generally exist in flavonoids ,chalcone and other natural products .Chalcone in isopentenyl and geranyl structure has anti‐cancer ,antioxidant activity which is popularly favored .There are domestic and foreign reports about many synthesis methods of prenylated and geranyl chalcone .In this paper ,two research directions from acetophenone or chalcone as raw material base are summarized ,making a summary on methods for synthesis of 3′,5′position as in isopentenyl or geranyl chalcones in recent years ,and providing more new methods for developing synthesis of 3′,5′position with reference to isopentenyl or geranyl chalcone.