中华实用儿科临床杂志
中華實用兒科臨床雜誌
중화실용인과림상잡지
Journal of Applied Clinical Pediatrics
2015年
5期
325-327
,共3页
急性肾损伤%生物标志物%早期诊断%儿童
急性腎損傷%生物標誌物%早期診斷%兒童
급성신손상%생물표지물%조기진단%인동
Acute kidney injury%Biomarker%Early diagnose%Child
急性肾损伤(AKI)是儿科临床常见的危急重症,发病率高、病死率高、预后差.目前诊断AKI的传统指标血肌酐和尿量不能早期诊断AKI.近年来,随着人们对于AKI的研究和认识不断深入,发现了许多特异性、灵敏性更高的生物学标志物.但是儿童AKI生物学标志物的研究滞后于成人,儿童AKI的病因、病理生理与成人相比有较大的差别.现就AKI生物学标志物在儿童AKI的研究进展做一介绍.
急性腎損傷(AKI)是兒科臨床常見的危急重癥,髮病率高、病死率高、預後差.目前診斷AKI的傳統指標血肌酐和尿量不能早期診斷AKI.近年來,隨著人們對于AKI的研究和認識不斷深入,髮現瞭許多特異性、靈敏性更高的生物學標誌物.但是兒童AKI生物學標誌物的研究滯後于成人,兒童AKI的病因、病理生理與成人相比有較大的差彆.現就AKI生物學標誌物在兒童AKI的研究進展做一介紹.
급성신손상(AKI)시인과림상상견적위급중증,발병솔고、병사솔고、예후차.목전진단AKI적전통지표혈기항화뇨량불능조기진단AKI.근년래,수착인문대우AKI적연구화인식불단심입,발현료허다특이성、령민성경고적생물학표지물.단시인동AKI생물학표지물적연구체후우성인,인동AKI적병인、병리생리여성인상비유교대적차별.현취AKI생물학표지물재인동AKI적연구진전주일개소.
Acute kidney injury(AKI) is a common clinical severe emergency in children,with high morbidity,mortality and poor prognosis.The traditional indicators such as serum creatinine and urine can't diagnose early.Recently,with the deepening research of AKI,many higher specific and sensitive biomarkers have been found.But the study of biomarkers in children is behind the adult,and the etiology,pathophysiology of AKI in children have great difference from adult.So this paper will show the advances of biomarkers in children of AKI.
