CAJ | 학술논문

目的探讨脑肿瘤患者围手术期认知功能障碍的临床特点.方法采用蒙特利尔认知量表对140例脑肿瘤患者进行手术前后认知功能评估.分析比较手术前后不同部位和不同病理类型认知功能状况及临床特征.结果 140例脑肿瘤患者中术前认知障碍病例数及患病率为83例(59.2％),评分(24.1±2.4)分.术后认知障碍病例数及患病率为113例(80.7％),评分(20.5±4.1)分.术后认知评分较术前明显降低(P＜0.05).恶性组与幕上脑肿瘤组术后认知障碍患病率分别明显高于术前(80.0％∶98.3％,71.8％:92.2％,均P＜0.05).结论脑肿瘤患者术前即存在着不同程度的认知功能障碍,恶性及幕上脑肿瘤者术后早期认知功能障碍较术前加重.
목적 탐토뇌종류환자위수술기인지공능장애적림상특점.방법 채용몽특리이인지량표대140례뇌종류환자진행수술전후인지공능평고.분석비교수술전후불동부위화불동병리류형인지공능상황급림상특정.결과 140례뇌종류환자중술전인지장애병례수급환병솔위83례(59.2％),평분(24.1±2.4)분.술후인지장애병례수급환병솔위113례(80.7％),평분(20.5±4.1)분.술후인지평분교술전명현강저(P＜0.05).악성조여막상뇌종류조술후인지장애환병솔분별명현고우술전(80.0％∶98.3％,71.8％:92.2％,균P＜0.05).결론 뇌종류환자술전즉존재착불동정도적인지공능장애,악성급막상뇌종류자술후조기인지공능장애교술전가중.
Objective To study the clinical characteristics of the perioperative cognitive dysfunction in brain tumor patients.Methods One hundred and forty cases of brain tumor patients were evaluated by using the Chinese vesion of Montreal Cognitive Assessment Questionnaire before and after surgery.The distribution and clinical features of cognitive dysfunction in different located lesions and pathological types were analyzed and compared.Results Among the 140 brain tumor patients,the preoperative cognitive impairment and prevalence rate were 59.2％,the score was 24.2 ± 2.4.The postoperative cognitive impairment and prevalence rate were 80.7％,the score was 20.5 ± 4.1.The postoperative cognitive dysfunction prevalence was significantly higher than the preoperative in benign and malignant with infra or supratentorial brain tumor patients(80.0％ vs 98.3％,71.8％ vs 92.2％,all P ＜0.05).Conclusions Vary different extent cognitive impairment was found in brain tumor patients in preoperative period.The postoperative cognitive dysfunction was seriously worse than that in the preoperative period in malignant and supratentorial brain tumors in earlier recovery period.