CAJ | 학술논문

目的：探讨儿童变应性鼻炎（AR）与腺样体肥大的关系，评价鼻用类固醇治疗儿童变应性鼻炎伴腺样体肥大的疗效。方法对照组为单纯腺样体生长儿童261例，其中腺样体肥大190例（72．7％）。观察组为变应性鼻炎伴腺样体生长儿童162例，其中腺样体肥大110例（67．2％）。两组均给予鼻用类固醇（丙酸氟替卡松喷剂）持续喷鼻3个月后于鼻内镜下复查。结果对照组并发腺样体肥大构成比为72．7％，观察组并发腺样体肥大构成比为67．2％，差异无统计学意义（χ2＝1．16，P ＞0．05）。对照组采用鼻用类固醇治疗后有效腺样体体积减少112例（58．9％），观察组有效腺样体体积减小89例（80．9％）（χ2＝19．04，P ＜0．01）。结论经鼻用类固醇治疗，变应性鼻炎伴腺样体肥大患儿腺样体体积减小程度较单纯腺样体肥大患儿明显。对变应性鼻炎合并腺样体肥大者可优先考虑应用鼻用类固醇激素。
목적：탐토인동변응성비염（AR）여선양체비대적관계，평개비용류고순치료인동변응성비염반선양체비대적료효。방법대조조위단순선양체생장인동261례，기중선양체비대190례（72．7％）。관찰조위변응성비염반선양체생장인동162례，기중선양체비대110례（67．2％）。량조균급여비용류고순（병산불체잡송분제）지속분비3개월후우비내경하복사。결과대조조병발선양체비대구성비위72．7％，관찰조병발선양체비대구성비위67．2％，차이무통계학의의（χ2＝1．16，P ＞0．05）。대조조채용비용류고순치료후유효선양체체적감소112례（58．9％），관찰조유효선양체체적감소89례（80．9％）（χ2＝19．04，P ＜0．01）。결론경비용류고순치료，변응성비염반선양체비대환인선양체체적감소정도교단순선양체비대환인명현。대변응성비염합병선양체비대자가우선고필응용비용류고순격소。
Objective To evaluate the curative effect of steroid nasal spray on pediatric allergic rhinitis with adenoidal hypertrophy.Methods A total of 261 children with adenoids served as the control group,of them,190 children (72.7%)were with adenoid hypertrophy.A total of 162 children with allergic rhinitis and adenoids served as the ex-perimental group,of them,110 children(67.2%)were with adenoid hypertrophy.The two groups were both treated by Fluticasone propionate nasal spray (50 μg per nostril a day)for 3 months.Results Adenoidal hypertrophy incidence was 72.7% in the control group and 67.2% in the experimental group (χ2 =1.16,P >0.05).112 (58.9%)patients in the control group and 89 (80.9%)patients in the experimental group had the adenoidal volume decreased (χ2 =19.04,P <0.01).Conclusion After steroid nasal spray treatment,the adenoidal volume is much more decreased in the experimental group than in the experimental group.Steroid nasal spray is the first choice for children with allergic rhinitis and adenoidal hypertrophy.