CAJ | 학술논문

目的：评估在新生儿脓毒症诊断时，PCT与C反应蛋白（CRP）、白细胞（WBC）计数相比所占的特殊优势。方法搜集2013年1月至2014年1月在辽宁省大连市中心医院的新生儿科住院的新生儿脓毒症的患儿46例，另选取50例同期住院非患新生儿脓毒症的新生儿作为对照组，入院时均做PCT ，CRP和WBC计数检查。结果两组WBC计数比较差异无统计学意义（P＞0．05），但 PCT、CRP检查差异均有统计学意义（P＜ 0．01），其中 PCT 诊断新生儿脓毒症的灵敏度（87％）明显高于CRP （63％），但是特异性（88％）略低于CRP（94％）。PCT约登指数明显高于CRP和WBC计数。结论 PCT在新生儿脓毒症诊断中优于CRP和WBC计数。
목적：평고재신생인농독증진단시，PCT여C반응단백（CRP）、백세포（WBC）계수상비소점적특수우세。방법수집2013년1월지2014년1월재요녕성대련시중심의원적신생인과주원적신생인농독증적환인46례，령선취50례동기주원비환신생인농독증적신생인작위대조조，입원시균주PCT ，CRP화WBC계수검사。결과량조WBC계수비교차이무통계학의의（P＞0．05），단 PCT、CRP검사차이균유통계학의의（P＜ 0．01），기중 PCT 진단신생인농독증적령민도（87％）명현고우CRP （63％），단시특이성（88％）략저우CRP（94％）。PCT약등지수명현고우CRP화WBC계수。결론 PCT재신생인농독증진단중우우CRP화WBC계수。
Objective To determine the special diagnostic superiority of PCT test over CRP and WBC count test for neonatal sepsis .Methods 46 newborn inpatients diagnosed neonatal sepsis in the neonatal department of Dalian Central Hospital from Janu‐ary 2013 to January 2014 and contemporaneous 50 uninfected neonatal inpatients as control group were collected .The PCT and CRP concentrations and WBC count were simultaneously measured at admission .Results The WBC count had no statistical difference between the two groups ,but the PCT and CRP detection showed the statistical difference between the two groups (P<0 .01) ,the sensitivity of PCT test was 87% ,which was significantly higher than 63% of CRP test ,but the specificity of PCT test was 87% , which was slightly lower than 90% of CRP test .The Youden index of PCT test was obviously higher than that of CRP test and WBC count .Conclusion PCT is superior to CRP and WBC count in diagnosing neonatal sepsis .