CAJ | 학술논문

目的：探讨脑膜转移瘤（MC）的MRI特征，及其瘤周水肿与血管内皮生长因子（VEGF）表达的相关关系。方法采用1．5 T磁共振仪平扫加增强观察48例MC 的MRI表现，对手术切除的瘤组织行VEGF免疫组化测定。结果48例MC患者的MRI特征表现为3型，瘤组织VEGF表达越强，瘤周水肿越重（χ2＝33．34，P＜0．01）。结论 MC的临床诊断中，MRI扫描不可或缺；其VEGF的表达和瘤周水肿产生呈正相关关系。
목적：탐토뇌막전이류（MC）적MRI특정，급기류주수종여혈관내피생장인자（VEGF）표체적상관관계。방법채용1．5 T자공진의평소가증강관찰48례MC 적MRI표현，대수술절제적류조직행VEGF면역조화측정。결과48례MC환자적MRI특정표현위3형，류조직VEGF표체월강，류주수종월중（χ2＝33．34，P＜0．01）。결론 MC적림상진단중，MRI소묘불가혹결；기VEGF적표체화류주수종산생정정상관관계。
Objective To discuss the MRI feature of meningeal metastasis and correlation of peritumoral brain edema and vascular endothelial growth factor(VEGF)expression.Methods 48 patients with meningeal metas-tasis were observed with plain and enhanced 1 .5 T magnetic resonance imaging scans,surgical removal of the tumor tissues was measured with VEGF immunohistochemistry.Results The patients with MC showed three types MRI fea-ture.The more vascular endothelial growth factor of the tumor tissues expressed,the more peritumoral brain edema (χ2 =33.34,P<0.01 ).Conclusion MRI scanning is necessary for clinical diagnosis in MC.There are positive correlation between the expression of vascular endothelial growth factor of the tumor tissues and peritumoral brain edema(P<0.01).