CAJ | 학술논문

目的：探究感觉神经元病的临床、生化、电生理特点。方法回顾性分析2008-2014年长海医院6例诊断为感觉神经元病患者的临床、生化、电生理资料。结果6例患者发病年龄50～70岁，平均61岁；男女比例为51；入院时大都表现为四肢深、浅感觉减退及感觉性共济失调、腱反射消失，神经电生理表现为广泛感觉神经动作电位减低或消失。可有脑脊液蛋白轻度升高。结论对伴有深、浅感觉受累，感觉神经动作电位的广泛性减低或消失的患者应考虑该病可能。
목적：탐구감각신경원병적림상、생화、전생리특점。방법회고성분석2008-2014년장해의원6례진단위감각신경원병환자적림상、생화、전생리자료。결과6례환자발병년령50～70세，평균61세；남녀비례위51；입원시대도표현위사지심、천감각감퇴급감각성공제실조、건반사소실，신경전생리표현위엄범감각신경동작전위감저혹소실。가유뇌척액단백경도승고。결론대반유심、천감각수루，감각신경동작전위적엄범성감저혹소실적환자응고필해병가능。
Objective To evaluate the clinical,biological,electrophysiological characteristics with sensory neuronopathies(SNN).Methods The clinical,biological,electrophysiological data of all patients who were diagnosed by specialists in Chang Hai Hospital from 2008 to 2014 were retrospectively analyzed.Results The age of onset were between 50 and 70 years old;the average was 61 yesars old;the male-to-female ratio was 51,on admission,the common manifest were the loss of superficial sense and deep sense with limbs,sensory ataxia,areflexia,nerve electro-physiology showed the reduce or disappear of sensory nerve action potential(SNAP),cerebrospinal showed moderately elevated protein.Conclusion SNN should be considered in those whose symptoms accompanying with superficial sense and deep sense damage and the reduce or disappear of sensory nerve action potential.