CAJ | 학술논문

目的对比128层双源CT不同对比剂注射方案在法洛四联症患儿血管造影中的图像质量.方法回顾分析2012年9月至2014年3月山东省医学影像学研究所60例超声心动图初诊法洛四联症未行手术治疗,需进一步明确心血管解剖结构的患儿的临床资料.患儿随机平均分为A、B、C3组,对比剂用量分别为1.2、1.2、1.5 ml/kg,对比剂注射时间分别为10、12、15 s.测量各组升主动脉(AA)、主肺动脉(MPA)、降主动脉(DA)、右心室(LV)的CT值及噪声,计算信噪比,并对图像质量进行主观评分.结果各测量部位的CT值、信噪比及主观评分组间差异无统计学意义,AA的CT值分别为(422±78)、(393±69)、(425±83) HU,MPA的CT值分别为(389±107)、(369±88)、(420±110) HU,DA的CT值分别为(437±112)、(418±97)、(438±117) HU,LV的CT值分别为(406±96)、(391±94)、(399±96) HU.B组图像均匀度(81±65)及上腔静脉硬化束伪影优于A、C两组(179±178、106±66),组间差异均有统计学意义(均P＜0.05).结论法洛四联症患儿行128层双源CT血管造影,1.2 ml/kg对比剂用量、12 s注射时间的对比剂注射方案可提高图像质量,具有良好的临床应用价值.
목적 대비128층쌍원CT불동대비제주사방안재법락사련증환인혈관조영중적도상질량.방법 회고분석2012년9월지2014년3월산동성의학영상학연구소60례초성심동도초진법락사련증미행수술치료,수진일보명학심혈관해부결구적환인적림상자료.환인수궤평균분위A、B、C3조,대비제용량분별위1.2、1.2、1.5 ml/kg,대비제주사시간분별위10、12、15 s.측량각조승주동맥(AA)、주폐동맥(MPA)、강주동맥(DA)、우심실(LV)적CT치급조성,계산신조비,병대도상질량진행주관평분.결과 각측량부위적CT치、신조비급주관평분조간차이무통계학의의,AA적CT치분별위(422±78)、(393±69)、(425±83) HU,MPA적CT치분별위(389±107)、(369±88)、(420±110) HU,DA적CT치분별위(437±112)、(418±97)、(438±117) HU,LV적CT치분별위(406±96)、(391±94)、(399±96) HU.B조도상균균도(81±65)급상강정맥경화속위영우우A、C량조(179±178、106±66),조간차이균유통계학의의(균P＜0.05).결론 법락사련증환인행128층쌍원CT혈관조영,1.2 ml/kg대비제용량、12 s주사시간적대비제주사방안가제고도상질량,구유량호적림상응용개치.
Objective To compare the image qualities of different contrast medium injection protocols for 128-slice dual-source computed tomography (DSCT) in children with Tetralogy of Fallot (TOF).Methods A total of 60 patients with TOF were randomly divided into groups A,B and C (n =20 each).And 128-slice DSCT angiography was performed with sequential mode according to the contrast injection protocols:the volume of contrast medium was 1.2,1.2 and 1.5 ml/kg and the injection time 10,12 and 15 s respectively.Contrast medium was followed by a saline bolus for 10 s.Enhancement and noise of ascending aorta,main pulmonary artery,descending aorta and left ventricle were quantified.Signal-to-noise ratio (SNR),dose-length product (DLP) and effective dose (ED) were calculated.The absolute difference of left and right ventricular attenuations was calculated to represent the image uniformity.Subjective image quality was assessed by two radiologists in consensus.Results No significant difference existed in attenuation or SNR between three groups in the same evaluated anatomic regions.No significant difference existed in image quality of heart chamber and great vessels.The image uniformity (81 ± 65) and subjective image quality of artifacts of superior vena cava were significantly better in group B than those in groups A and C (179 ± 178,106 ± 66,P ＜ 0.05).Conclusion The contrast medium injection protocol of 1.2 ml/kg volume contrast medium injected within 12 s may enhance the image quality of 128-slice dual-source CT in children with TOF.