世界最新医学信息文摘（连续型电子期刊）
世界最新醫學信息文摘（連續型電子期刊）
세계최신의학신식문적（련속형전자기간）
World Latest Medicine Information
2015年
9期
23-24
,共2页
小细胞低色素性贫血%血清铁%铁蛋白%血清可溶性转铁蛋白受体%细胞内铁细胞外铁%环形铁幼粒细胞
小細胞低色素性貧血%血清鐵%鐵蛋白%血清可溶性轉鐵蛋白受體%細胞內鐵細胞外鐵%環形鐵幼粒細胞
소세포저색소성빈혈%혈청철%철단백%혈청가용성전철단백수체%세포내철세포외철%배형철유립세포
Microcytic hypochromic anemia%Serum ironFerritin%Serum soluble transferrin receptor%Intracellular iron Extracellular iron%Annular iron promyelocytic
目的：评价SI、SF、sTfR、细胞内铁、细胞外铁及环形铁幼粒细胞在小细胞低色素性贫血鉴别诊断中的应用价值。方法随机选出缺铁性贫血30例、地中海贫血28例、慢性疾病性贫血31例、铁粒幼细胞性贫血27例，同时选30例健康成人为对照组，检测四组患者及正常对照组中SI、SF、sTfR及细胞内、外铁各项指标的检测结果，对检测数据进行t检验和相关分析。结果 IDA组与ACD组的SI、SF都低于正常对照组、地中海贫血组和SA组的SI、SF，差异有统计学意义（P值<0.05），IDA组的sTfR高于正常对照组、ACD和SA组的sTfR，差异有统计学意义（P值<0.05）；IDA组的内铁明显低于其他组的，细胞外铁减少或消失；地中海贫血组的sTfR明显高于SA组的，差异有统计学意义（P值<0.05），而SA组的环形铁幼粒细胞易见占15%以上，明显高于地贫组及其他组的，差异有统计学意义（P值<0.05）。结论 SI检测是常规检测贫血首选初筛指标，SF、sTfR是IDA与ACD的鉴别诊断的常用指标，细胞内、外铁是鉴别IDA的金指标。sTfR和环形铁幼粒细胞计数可用于地贫与铁粒幼细胞贫血的鉴别诊断。
目的：評價SI、SF、sTfR、細胞內鐵、細胞外鐵及環形鐵幼粒細胞在小細胞低色素性貧血鑒彆診斷中的應用價值。方法隨機選齣缺鐵性貧血30例、地中海貧血28例、慢性疾病性貧血31例、鐵粒幼細胞性貧血27例，同時選30例健康成人為對照組，檢測四組患者及正常對照組中SI、SF、sTfR及細胞內、外鐵各項指標的檢測結果，對檢測數據進行t檢驗和相關分析。結果 IDA組與ACD組的SI、SF都低于正常對照組、地中海貧血組和SA組的SI、SF，差異有統計學意義（P值<0.05），IDA組的sTfR高于正常對照組、ACD和SA組的sTfR，差異有統計學意義（P值<0.05）；IDA組的內鐵明顯低于其他組的，細胞外鐵減少或消失；地中海貧血組的sTfR明顯高于SA組的，差異有統計學意義（P值<0.05），而SA組的環形鐵幼粒細胞易見佔15%以上，明顯高于地貧組及其他組的，差異有統計學意義（P值<0.05）。結論 SI檢測是常規檢測貧血首選初篩指標，SF、sTfR是IDA與ACD的鑒彆診斷的常用指標，細胞內、外鐵是鑒彆IDA的金指標。sTfR和環形鐵幼粒細胞計數可用于地貧與鐵粒幼細胞貧血的鑒彆診斷。
목적：평개SI、SF、sTfR、세포내철、세포외철급배형철유립세포재소세포저색소성빈혈감별진단중적응용개치。방법수궤선출결철성빈혈30례、지중해빈혈28례、만성질병성빈혈31례、철립유세포성빈혈27례，동시선30례건강성인위대조조，검측사조환자급정상대조조중SI、SF、sTfR급세포내、외철각항지표적검측결과，대검측수거진행t검험화상관분석。결과 IDA조여ACD조적SI、SF도저우정상대조조、지중해빈혈조화SA조적SI、SF，차이유통계학의의（P치<0.05），IDA조적sTfR고우정상대조조、ACD화SA조적sTfR，차이유통계학의의（P치<0.05）；IDA조적내철명현저우기타조적，세포외철감소혹소실；지중해빈혈조적sTfR명현고우SA조적，차이유통계학의의（P치<0.05），이SA조적배형철유립세포역견점15%이상，명현고우지빈조급기타조적，차이유통계학의의（P치<0.05）。결론 SI검측시상규검측빈혈수선초사지표，SF、sTfR시IDA여ACD적감별진단적상용지표，세포내、외철시감별IDA적금지표。sTfR화배형철유립세포계수가용우지빈여철립유세포빈혈적감별진단。
Objective:To evaluate the application value of SI, SF, sTfR,intracellular, extracellular iron and iron ring iron promyelocytic in cellule low pigment anaemia in differential diagnosis.Methods: randomly selected30 cases of iron deifciency anemia, thalassemia, 28 cases of anemia of chronic disease in 31 cases, sideroblastic anemia in 27 cases, and 30 healthy adult as control group, the detection results of testing of the indicators of four groups of patients and in normal control group SI, SF,sTfR and intracellular, extracellular iron, t test and correlation analysis oftest data.Results: IDA group and ACD group, SI, SF were lower than those of the normal control group, the Mediterranean anemia group and the SA group of SI, SF, the difference was statistically signiifcant (P value <0.05), the IDA group of sTfR is higher than the normal control group,ACD and SA in group sTfR, the difference was statistically significant (Pvalue <0.05); IDA in the iron group was significantly lower than other groups, extracellular iron decreased or disappeared; SA group ofMediterranean anemia group was signiifcantly higher than that of thesTfR, the difference was statistically signiifcant (P value <0.05), and group SA of the annular iron promyelocytic easily see accounted for more than 15%, signiifcantly higher than that of thalassemia group and othergroups, the difference was statistical signiifcance (P = <0.05).Conclusion: the detection of SI is the preferred routine detection of anemia screeningindex, SF, sTfR is a common index of differential diagnosis of IDA and ACD, iron within the cell, is the gold index for differential IDA. STfR and annular iron immature granulocyte count can be used for differential diagnosis of thalassemia with sideroblastic anemia.
