CAJ | 학술논문

目的观察子宫肌瘤和子宫腺肌瘤高强度聚焦超声(HIFU)治疗效果.方法对2011年7月至2013年11月石家庄市第一医院就诊临床诊断为子宫肌瘤和子宫腺肌瘤的166例患者行HIFU治疗,于治疗后1、3和6个月分别对患者进行随访及超声复查;观察子宫肌瘤及子宫腺肌瘤患者治疗前后临床症状、血流情况、MRI平扫病灶体积大小等指标.结果 HIFU治疗后患者月经量明显减少,血红蛋白全部恢复正常,痛经等临床症状明显改善,患者子宫消融灶明显缩小,治疗后1、3及6个月消融灶治疗有效率分别为71.8％、86.1％、95.4％,血流明显减少或消失,无一例出现不可接受的不良反应发生.结论采用HIFU技术对子宫肌瘤和子宫腺肌瘤患者进行微无创消融治疗安全有效,不良反应小,有利于疗效观察.
목적 관찰자궁기류화자궁선기류고강도취초초성(HIFU)치료효과.방법 대2011년7월지2013년11월석가장시제일의원취진림상진단위자궁기류화자궁선기류적166례환자행HIFU치료,우치료후1、3화6개월분별대환자진행수방급초성복사;관찰자궁기류급자궁선기류환자치료전후림상증상、혈류정황、MRI평소병조체적대소등지표.결과 HIFU치료후환자월경량명현감소,혈홍단백전부회복정상,통경등림상증상명현개선,환자자궁소융조명현축소,치료후1、3급6개월소융조치료유효솔분별위71.8％、86.1％、95.4％,혈류명현감소혹소실,무일례출현불가접수적불량반응발생.결론 채용HIFU기술대자궁기류화자궁선기류환자진행미무창소융치료안전유효,불량반응소,유리우료효관찰.
Objective To explore the validity of high intensive focused ultrasound (HIFU) in the treatment of uterus myoma and adenomyoma.Methods A total of 166 patients with uterus myoma and adenomyoma received HIFU treatment from July 2011 to November 2013 at our hospital.The follow-ups were conducted at 1,3,6 month post-treatment.Their status of clinical symptoms,tumor volume,blood flow and efficacy of HIFU were evaluated.Results Menstrual blood decreased after treatment.The levels of hemoglobin all returned to normal in anemic patients and dysmenorrhea showed great improvement.Ultrasound showed that uterine ablation lesions significantly diminished after treatment.The effective rate was 71.8％ at 1 month,86.1％ at 3 month and 95.4％ at 6 month post-treatment and blood flow within ablation lesions decreased after treatment.None of unacceptable side effects occurred.Conclusion HIFU treatment of uterus myoma and adenomyoma is both feasible and safe with fewer side effects.