CAJ | 학술논문

目的：探讨血浆溶血磷脂酸（LPA ）测定及简易精神状态量表（MMSE）评分在门诊头晕患者风险的判断效果。方法：选择脑缺血导致头晕的对照组患者80例及高血压导致头晕的观察组患者80例，均行血浆 LPA 测定、MMSE 评分及相关性分析。结果：观察组患者血浆 LPA 浓度明显低于对照组，观察组 MMSE 总分、定点、记忆、注意、语言、抽象、执行评分明显低于对照组，差异有统计学意义（P＜0．05）。观察组认知功能缺损发生率明显高于对照组（P ＜0．05），多因素相关性分析显示血浆 LPA 与脑缺血是影响头晕门诊认知功能缺损的主要独立危险因素（P ＜0．05）。结论：血浆 LPA 测定及 MMSE 评分在门诊头晕患者的风险判断中有很好的价值，能有效区分头晕成因，联合检测两者水平可作为脑缺血与高血压的预测指标。
목적：탐토혈장용혈린지산（LPA ）측정급간역정신상태량표（MMSE）평분재문진두훈환자풍험적판단효과。방법：선택뇌결혈도치두훈적대조조환자80례급고혈압도치두훈적관찰조환자80례 ，균행혈장 LPA 측정、MMSE 평분급상관성분석。결과：관찰조환자혈장 LPA 농도명현저우대조조，관찰조 MMSE 총분、정점、기억、주의、어언、추상、집행평분명현저우대조조，차이유통계학의의（P＜0．05）。관찰조인지공능결손발생솔명현고우대조조（P ＜0．05），다인소상관성분석현시혈장 LPA 여뇌결혈시영향두훈문진인지공능결손적주요독립위험인소（P ＜0．05）。결론：혈장 LPA 측정급 MMSE 평분재문진두훈환자적풍험판단중유흔호적개치，능유효구분두훈성인，연합검측량자수평가작위뇌결혈여고혈압적예측지표。
Objective :To investigate the clinic risk judgment effects for dizziness patients by the blood LPA values and MMSE scores .Methods :Selected 80 cases of cerebral ischemia leads to dizziness as the control group ,80 cases of hypertension leads to dizziness as the observation group ,all cases were given blood LPA values and MMSE scores measured and analyzed .Results :The plasma LPA concentrations of the observation group were significantly lower than those in the control group ,the MMSE total scores ,location ,memory ,attention ,lan‐guage ,ABSTRACT ,execution scores of the observation group were significantly lower than those in the control group ,the difference had statistically significant were compared (P < 0 .05 ) .The incidence of cognitive deficits of the observed group were significantly higher (P < 0 .05) ,multivariate analysis showed that plasma LPA and cere‐bral ischemia were the major independent risk factors for cognitive deficits (P < 0 .05 ) .Conclusion :Blood LPA values and MMSE scores for judging dizziness can effectively distinguish the causes ,its joint detection can be used as predictors of cerebral ischemia and hypertension .