CAJ | 학술논문

目的：探讨红细胞分布宽度（ RDW）与冠状动脉粥样硬化性心病（冠心病）冠状动脉病变程度的相关性。方法将697例患者根据冠脉造影结果分为冠心病组453例和非冠心病组244例，比较2组患者的临床资料，并对冠心病危险因素进行多元logistic回归分析。结果冠心病组RDW水平高于非冠心病组，多元logistic回归分析显示RDW值与冠心病独立相关；以冠脉病变支数将所有患者分为4组进行RDW值比较，发现随着病变支数增加，RDW值逐渐升高；多元逐步回归分析显示RDW值与冠心病冠脉病变严重程度独立相关，RDW值越高，冠脉病变越严重（β＝0？．282， P ＝0．000）。结论 RDW与冠心病冠脉病变严重程度密切相关，RDW升高可能是冠心病冠脉病变严重程度的一个预测指标。
목적：탐토홍세포분포관도（ RDW）여관상동맥죽양경화성심병（관심병）관상동맥병변정도적상관성。방법장697례환자근거관맥조영결과분위관심병조453례화비관심병조244례，비교2조환자적림상자료，병대관심병위험인소진행다원logistic회귀분석。결과관심병조RDW수평고우비관심병조，다원logistic회귀분석현시RDW치여관심병독립상관；이관맥병변지수장소유환자분위4조진행RDW치비교，발현수착병변지수증가，RDW치축점승고；다원축보회귀분석현시RDW치여관심병관맥병변엄중정도독립상관，RDW치월고，관맥병변월엄중（β＝0？．282， P ＝0．000）。결론 RDW여관심병관맥병변엄중정도밀절상관，RDW승고가능시관심병관맥병변엄중정도적일개예측지표。
Objective To explore the correlation between red blood cell distribution width ( RDW) and the severity of coronary lesions .Methods According to the results of coronary angiography ,the 697 patients were divided into coronary heart disease group ( n =453 ) and non-coronary heart disease group ( n =244 ) .The clinical data were compared between two groups and risk factors of coronary heart disease were analyzed by multivariant logistic regression analysis .Results The levels of RDW in coronary heart disease group were significantly higher than those in non -coronary heart disease group .RDW values were increased with the increase of coronary lesions severity .Multivariant logistic regression analysis showed that RDW value was independently associated with coronary heart disease and the severity of coronary lesions .The higher RDW values , the severer coronary lesions (β=0.282, P <0.01).Conclusion RDW is closely correlated with the severity of coronary le-sions,and the increase of RDW may be an independent predictor for the severity of coronary heart disease .